Protein Alignment IGSF9B and rst

DIOPT Version :9

• Sequence 1: NP_001264214.1
• Gene: IGSF9B / 22997
• HGNCID: 32326
• Length: 1437
• Species: Homo sapiens
• Sequence 2: NP_001284835.1
• Gene: rst / 31290
• FlyBaseID: FBgn0003285
• Length: 764
• Species: Drosophila melanogaster
• Alignment Length: 987
• Identity: 183/987 - (18%)
• Similarity: 298/987 - (30%)
• Gaps: 347/987 - (35%)

Human    29 EPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFK--FGV----PIPIFIKFGYYPPHVDPEYA 87
            ||:..||..|..|.|.|.||:      ....::|.|  ||:    .:..|.::.......:.:|
  Fly    33 EPQDQTAVVGARVTLPCRVIN------KQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDY- 90

Human    88 GRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTE-TPPQYIEA 151
                     ||.:..|..:|...|:|:|....:......: ::..||:..||...: |....|.|
  Fly    91 ---------SLDIYPVMLDDDARYQCQVSPGPEGQPAIRS-TFAGLTVLVPPEAPKITQGDVIYA 145

Human   152 KEGGSITMTCTAF-GNPKPIVTWLKE-GTLLGASGKYQV----------SDGSLTVTSVSREDRG 204
            .|...:.:.|.:. |.|...:||:.. |.:|..:.:|.|          :...|.:|........
  Fly   146 TEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNT 210

Human   205 AYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNI--------------------------- 242
            .::|:|.:.......:..:.|:     |.....:.||:
  Fly   211 NFSCQAQNTADRTYRSAKIRVE-----VKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSR 270

Human   243 ---SQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCV 304
               .....|.|||:|.|.::.|.|:..||.:......::.:|.:         .:........|.
  Fly   271 IVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNV---------TRKFHDAIVKCE 326

Human   305 PSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKW--NKDGRPLQ 367
            ..||:|:|.. |..|.:.|.......|..:...||....:.|.||:.|...:| |  :...|.:.
  Fly   327 VQNSVGKSED-SETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIV-WIQHPSDRVVG 389

Human   368 VEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQ 432
            ...||.:::           :.|..|.|.| ..|..|....||.|.:.||..|
  Fly   390 TSTNLTFSV-----------SNETAGRYYC-KANVPGYAEISADAYVYLKGSP------------ 430

Human   433 EAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSI 497
                                              |:.|...|:..:.  |....||.|::|
  Fly   431 ----------------------------------AIGSQRTQYGLVG--DTARIECFASSV---- 455

Human   498 TASTHLTVIGTSPHAPGSVRVQVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSL--PV 560
                        |.|            .:|||          ||:.....::.| ||:..|  .|
  Fly   456 ------------PRA------------RHVSW----------TFNGQEISSESG-HDYSILVDAV 485

Human   561 PPGPSWLLVDTLEPETAYQF----------------SVLAQNKLGTSAFSEVV-TVNTLAFPITT 608
            |.|....|:  :....||.:                .:..|.|...|....:| .::.:||.:..
  Fly   486 PGGVKSTLI--IRDSQAYHYGKYNCTVVNDYGNDVAEIQLQAKKSVSLLMTIVGGISVVAFLLVL 548

Human   609 PEPLVLVTPPRCLIANRTQQGVLLSWLPPANHSFPIDRYIMEFRVAERWELLDDGI-----PGTE 668
              .:::|...:|  ..||:       ||||:       .|.|.::.:     :.|:     ||..
  Fly   549 --TILVVVYIKC--KKRTK-------LPPAD-------VISEHQITK-----NGGVSCKLEPGDR 590

Human   669 GEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTEDGLARPVLAGIVATICF 733
            ...:: ||..|              ||......|..||...|.|.                   :
  Fly   591 TSNYS-DLKVD--------------ISGGYVPYGDYSTHYSPPPQ-------------------Y 621

Human   734 LAAAILFSTLAACFV--NKQRKRKLKRKKD----------PPLSITHCRKSLESPLSSGKVSPES 786
            |......|..::..:  |.|.:.:|::::.          ..|.:|....|....|:...:....
  Fly   622 LTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQTTTLPMTFLTNSSGGSLTGSIIGSRE 686

Human   787 IRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSKKYSVAKAEAEAEATTPIELIS 851
            ||         .|.|.|              ||...|...:||........::...|||..
  Fly   687 IR---------QDNGLP--------------SLQSTTASVVSSSPNGSCSNQSTTAATTTT---- 724

Human   852 RGPDGRFVMDPAEMEPSLKSR--RIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKSQLTP 914
                 ..|:.|:.|..|:..|  .|.|.|:
  Fly   725 -----THVVVPSSMALSVDPRYSAIYGNPY----------------------------------- 749

Human   915 LSSSQESYLPPP 926
            |.||..|.||||
  Fly   750 LRSSNSSLLPPP 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGSF9B	NP_001264214.1	IG_like	30..115	CDD:214653	21/90 (23%)
		Ig	41..115	CDD:143165	17/79 (22%)
		I-set	139..225	CDD:254352	18/98 (18%)
		IGc2	153..210	CDD:197706	13/68 (19%)
		I-set	229..321	CDD:254352	21/121 (17%)
		Ig	235..321	CDD:299845	20/115 (17%)
		IG_like	331..414	CDD:214653	21/84 (25%)
		Ig	<353..414	CDD:299845	14/62 (23%)
		IG_like	426..505	CDD:214653	8/78 (10%)
		Ig	442..505	CDD:299845	8/62 (13%)
		FN3	510..601	CDD:238020	21/109 (19%)
		FN3	617..699	CDD:238020	17/86 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	758..817		9/68 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	911..1081		8/16 (50%)
rst	NP_001284835.1	IG_like	34..130	CDD:214653	24/112 (21%)
		Ig	42..114	CDD:299845	19/87 (22%)
		C2-set_2	135..225	CDD:285423	17/89 (19%)
		Ig_3	265..329	CDD:290638	12/72 (17%)
		I-set	346..420	CDD:254352	18/86 (21%)
		Ig	360..425	CDD:299845	19/77 (25%)
		Ig5_KIRREL3-like	428..524	CDD:143235	26/184 (14%)
		IG_like	435..524	CDD:214653	23/131 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810