Sequence 1: | NP_036440.1 | Gene: | KDM2A / 22992 | HGNCID: | 13606 | Length: | 1162 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001262400.1 | Gene: | Kdm2 / 41090 | FlyBaseID: | FBgn0037659 | Length: | 1345 | Species: | Drosophila melanogaster |
Alignment Length: | 1405 | Identity: | 470/1405 - (33%) |
---|---|---|---|
Similarity: | 642/1405 - (45%) | Gaps: | 351/1405 - (24%) |
- Green bases have known domain annotations that are detailed below.
Human 1 MEPEEERIRYSQRLRGTMRRRY-EDDGISDDEIEGKRTFDLEEKLHTNKY-NANFVTFMEGKDFN 63
Human 64 VEYIQRGGLRDPLIFKNSDGLGIKMPDP-DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWT 127
Human 128 RYYETPEEEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQ 192
Human 193 YPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIF 257
Human 258 LGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPN 322
Human 323 KFRYPFYYEMCWYVLERYVYCITNRSHLTKEFQKESLSMDLELNGLESGNGDEEAVDREPRRLSS 387
Human 388 RRSVLTSPVANGVNLDYDGLGKTCRSLPSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVH 452
Human 453 LTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELANSDPKLALTGVPIVQWP 517
Human 518 KRDKLKFPTRPKVRV-------------------------------------------------- 532
Human 533 -----------------------------------PTIPITKPHTMKPAPRLT------------ 550
Human 551 PVRPAAASPI--------------VSGA------------------------------------- 564
Human 565 -----------RRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSV 618
Human 619 TCSLCGEVDQNEET-----------QDFEKKLMECCICNEIVHPGCL--QMDG-------EGLLN 663
Human 664 EELPNCWECPKCYQEDSSEKAQKR--KMEESDEEAVQAKVLRPLRSCD-----EPLTPPPHSP-- 719
Human 720 ----TSMLQLIHDPVSPRGMVTR-----------------------SSPGAGPSDHHSASRDERF 757
Human 758 KRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHG-----TSIVP 817
Human 818 KL-QAITASSANLRHSPRVLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSA----------- 870
Human 871 ---EEGGAARLNGRGSWAQDGDESW-MQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWT 931
Human 932 KIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALS 996
Human 997 TSSCPLLRTLDLRWAVGIKDPQIRDLLTPPAD-KPG-QDNRSKLRNMTDFRLAGLDITDATLRLI 1059
Human 1060 IRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYS--LTELNMAGCNKLTDQTLIYLRRIANVT 1122
Human 1123 LIDLRGCKQITRKACEHFISDLSINSLY--CLSDEKLIQK 1160 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KDM2A | NP_036440.1 | cupin_like | 199..299 | CDD:328732 | 73/99 (74%) |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 367..389 | 0/21 (0%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 532..557 | 8/121 (7%) | |||
zf-CXXC | <576..609 | CDD:251032 | 19/32 (59%) | ||
PHD_KDM2A | 619..675 | CDD:277113 | 28/75 (37%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 704..789 | 20/118 (17%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 839..887 | 10/61 (16%) | |||
F-box-like | 896..934 | CDD:315592 | 15/37 (41%) | ||
leucine-rich repeat | 930..954 | CDD:275381 | 7/23 (30%) | ||
AMN1 | 932..1138 | CDD:332986 | 85/209 (41%) | ||
leucine-rich repeat | 955..978 | CDD:275381 | 13/22 (59%) | ||
LRR 1 | 961..982 | 14/20 (70%) | |||
leucine-rich repeat | 979..1002 | CDD:275381 | 11/22 (50%) | ||
LRR 2 | 984..1010 | 14/25 (56%) | |||
leucine-rich repeat | 1003..1040 | CDD:275381 | 18/38 (47%) | ||
leucine-rich repeat | 1041..1065 | CDD:275381 | 8/23 (35%) | ||
LRR 3 | 1048..1073 | 11/24 (46%) | |||
leucine-rich repeat | 1066..1095 | CDD:275381 | 11/28 (39%) | ||
LRR 4 | 1074..1103 | 11/30 (37%) | |||
leucine-rich repeat | 1096..1120 | CDD:275381 | 8/23 (35%) | ||
LRR 5 | 1104..1128 | 5/23 (22%) | |||
leucine-rich repeat | 1121..1140 | CDD:275381 | 4/18 (22%) | ||
LRR 6 | 1129..1156 | 7/28 (25%) | |||
Kdm2 | NP_001262400.1 | cupin_like | 231..331 | CDD:304367 | 73/99 (74%) |
PRTases_typeI | <394..>467 | CDD:294217 | 32/74 (43%) | ||
zf-CXXC | 670..716 | CDD:251032 | 26/45 (58%) | ||
PHD_4 | 721..801 | CDD:293471 | 30/80 (38%) | ||
F-box-like | <1073..1108 | CDD:289689 | 14/34 (41%) | ||
leucine-rich repeat | 1102..1125 | CDD:275381 | 7/23 (30%) | ||
leucine-rich repeat | 1126..1149 | CDD:275381 | 13/22 (59%) | ||
leucine-rich repeat | 1150..1173 | CDD:275381 | 11/22 (50%) | ||
AMN1 | 1166..>1320 | CDD:187754 | 59/160 (37%) | ||
leucine-rich repeat | 1174..1213 | CDD:275381 | 18/38 (47%) | ||
leucine-rich repeat | 1214..1238 | CDD:275381 | 8/23 (35%) | ||
leucine-rich repeat | 1239..1267 | CDD:275381 | 11/30 (37%) | ||
leucine-rich repeat | 1268..1292 | CDD:275381 | 8/23 (35%) | ||
leucine-rich repeat | 1293..1317 | CDD:275381 | 7/27 (26%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 255 | 1.000 | Domainoid score | I2050 |
eggNOG | 1 | 0.900 | - | - | E1_KOG1633 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H56564 | |
Inparanoid | 1 | 1.050 | 814 | 1.000 | Inparanoid score | I484 |
Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3167 |
OMA | 1 | 1.010 | - | - | QHG50015 | |
OrthoDB | 1 | 1.010 | - | - | D165446at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0000253 | |
OrthoInspector | 1 | 1.000 | - | - | otm41017 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_104082 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR23123 |
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R626 |
SonicParanoid | 1 | 1.000 | - | - | X1005 | |
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
16 | 15.910 |