Protein Alignment DIP2C and Acsx1L

DIOPT Version :10

• Sequence 1: XP_054221234.1
• Gene: DIP2C / 22982
• HGNCID: 29150
• Length: 1626
• Species: Homo sapiens
• Sequence 2: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 153/648 - (23%)
• Similarity: 245/648 - (37%)
• Gaps: 182/648 - (28%)

Human  1022 DNDQ--------ARKF---LFLSEVLQWRAQTTPDHILYTLLNCRGAIANSLTCVQLHKRAEKIA 1075
            ||||        .:.|   |.:.|::....:..| .:...:....|.:   ||..:|...|.::|
  Fly    10 DNDQKIWSGEPVVKYFDPDLSIGEIIFHEMRRHP-QLTAQISATEGTV---LTRGELLANAMRLA 70

Human  1076 VMLMERGHLQDGDHVALVYPPGIDLIAAFYGCLYAGCVPITVRPPHPQNIATTLPTVKMIVEVSR 1140
            ..:...|.|| .|.|.::......::|..|.|.:.|..      .|..||.....|::.|.:|:|
  Fly    71 SYMRSLGLLQ-SDIVGIIGRNTTHMLAVAYACFFNGIA------FHSLNITYDRDTIEKIYKVTR 128

Human  1141 SACLMTTQLIC---KLLRSREAAAAVDV-----RTWPL-------ILDTDDLPKKRPAQICKPCN 1190
            .:.     :.|   :..:.|.|.|.:||     |..||       ::.|......:||::.|. |
  Fly   129 PSI-----IFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKIDEVVATPIEENFQPAKLEKG-N 187

Human  1191 PDTLAYLDFSVSTTG------------MLAG--------VKMSHAATSAFCRSIKLQCELYPSRE 1235
            ..|||.| .|..|||            :|||        |:.||..
  Fly   188 DQTLAIL-CSSGTTGTPKAVTITNSRHILAGNYHLTTADVQYSHNT------------------- 232

Human  1236 VAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCT 1300
                ||...||      |.::.||..|.....::...:||..|..:.:|||..|....|.|.|..
  Fly   233 ----LDWITGL------LTTITSGVFSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSMALMI 287

Human  1301 KGLGSQTESLKARGLDLSRVRTCVVVAEERPRIALTQSF-SKLFKDLGLHPRAVSTSFGCRVNLA 1364
            .....:|       .|:|.:| |.:....|..:.:.:.. |:|..|
  Fly   288 NCPDFET-------CDMSSLR-CYMFGGSRAALEVQKGIRSRLSHD------------------- 325

Human  1365 ICLQPHRLWTLAEQGTSGPDPTTVY--VDMRALRHDRVRLVER-GSPHSLPLMESGKILPGVRII 1426
             |||                  .||  .::.|:........|: ||        .|:::.|:::.
  Fly   326 -CLQ------------------FVYGFTELGAMATINCHFDEKTGS--------VGQLVNGLKMK 363

Human  1427 IANPETKGPLGDSHLGEIWVHSAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFL 1491
            |.|.:.:. ||...:||:.:.:..:.|||   ||:|   .:..|.|.|.|     |..:|.||::
  Fly   364 IINDDGES-LGPDEIGEVCIMNNQHWSGY---YGNE---VETRNMRDSLG-----WYHSGDLGYM 416

Human  1492 RRTELTDANGERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVF-TWTNLL--- 1552
                      :|...||::....|.::.:.:.|:|.||| |||.....|.|..|| .|:|:.
  Fly   417 ----------DRDGFLYIMDRKKEMLKYQNIMYYPNDIE-SVISEMPQVAEVCVFGIWSNIFGDE 470

Human  1553 --VVVVELDGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFL 1613
              ..||:..|||.||.|:|..|.:....::..:.|..|:||  .:..::.|:..||..:..||
  Fly   471 AAAAVVKKLGSELEAQDVVDYVRSRTDSKYKQLNGGAVIVD--DLQRSANGKTNRMANKAYFL 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP2C	XP_054221234.1	DMAP_binding	<32..178	CDD:368923
		Dip2	396..972	CDD:341231
		Dip2	1048..1622	CDD:341231	145/611 (24%)
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	141/599 (24%)