Protein Alignment SCMH1 and Scmh1

DIOPT Version :10

• Sequence 1: NP_001381240.1
• Gene: SCMH1 / 22955
• HGNCID: 19003
• Length: 670
• Species: Homo sapiens
• Sequence 2: XP_038966228.1
• Gene: Scmh1 / 362581
• RGDID: 1305788
• Length: 718
• Species: Rattus norvegicus
• Alignment Length: 670
• Identity: 616/670 - (91%)
• Similarity: 636/670 - (94%)
• Gaps: 6/670 - (0%)

Human     6 IDWSDVRKHKYGHLSESASQYQEAADILDLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKI 70
            :||:||:|.||||||||||||||..|||:|||||||||||||.||||||||||||||||||||||
  Rat    50 VDWNDVKKPKYGHLSESASQYQEPVDILELGHFTWDKYLKETSSVPAPVHCFKQSYTPPSNEFKI 114

Human    71 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSAEIQPIGNCEKNGGMLQP 135
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||
  Rat   115 SMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQP 179

Human   136 PLGFRLNASSWPMFLLKTLNGAEMAPIRIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIG 200
            |||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||
  Rat   180 PLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIG 244

Human   201 EVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPYPASDVNTEK 265
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||.|:|||:|||
  Rat   245 EVRGSEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPSPSSDVSTEK 309

Human   266 PSIHSSTKTVLEHQPGQRGRKPGKKRGRTPKTLISHPISAPSKTAEPLKFPKKRGPKPGSKRKPR 330
            ||| :|||||||.||||||||||||||||||.||.||.|.|||:||||||||||||||||||:||
  Rat   310 PSI-NSTKTVLEPQPGQRGRKPGKKRGRTPKILIPHPTSTPSKSAEPLKFPKKRGPKPGSKRRPR 373

Human   331 TLLNPPPASPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKNGSTGPHLDKKKVQQLPDHF 395
            |||:|||.|||||||||||||||||||||||||||||||||||||:|||||||||||:|||||||
  Rat   374 TLLSPPPTSPTTSTPEPDTSTVPQDAATIPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHF 438

Human   396 GPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFL 460
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   439 GPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFL 503

Human   461 EKLCHNLRSDNLFGNQPFTQTHLSLTAIEYSHSHDRYLPGETFVLGNSLARSLEPHSDSMDSASN 525
            ||||||||||||||||||||||:||||.||||.||||||||||||||||.||||.|||.||||..
  Rat   504 EKLCHNLRSDNLFGNQPFTQTHVSLTATEYSHGHDRYLPGETFVLGNSLTRSLETHSDLMDSALK 568

Human   526 PTNLVSTSQR-----HRPLLSSCGLPPSTASAVRRLCSRGVLKGSNERRDMESFWKLNRSPGSDR 585
            |.|||||||.     :||||.|||||.||.||||||||||||||:.||||:|||||||.||||||
  Rat   569 PANLVSTSQTLRTPGYRPLLPSCGLPLSTVSAVRRLCSRGVLKGTRERRDVESFWKLNHSPGSDR 633

Human   586 YLESRDASRLSGRDPSSWTVEDVMQFVREADPQLGPHADLFRKHEIDGKALLLLRSDMMMKYMGL 650
            :|||||..|||||||||||||||||||||||||||.|||||||||||||||||||||||||||||
  Rat   634 HLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLGSHADLFRKHEIDGKALLLLRSDMMMKYMGL 698

Human   651 KLGPALKLSYHIDRLKQGKF 670
            |||||||||:||||||||||
  Rat   699 KLGPALKLSFHIDRLKQGKF 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCMH1	NP_001381240.1	MBT_SCMH1_rpt1	37..167	CDD:439095	126/129 (98%)
		MBT_SCMH1_rpt2	172..246	CDD:439098	73/73 (100%)
		PHA03247	<243..367	CDD:223021	109/123 (89%)
		RBR	281..334	CDD:465382	46/52 (88%)
		SLED	368..476	CDD:463469	105/107 (98%)
		SAM_Scm	597..667	CDD:188977	67/69 (97%)
Scmh1	XP_038966228.1	MBT_SCMH1_rpt1	81..211	CDD:439095	126/129 (98%)
		MBT_SCMH1_rpt2	216..290	CDD:439098	73/73 (100%)
		RBR	324..373	CDD:465382	42/48 (88%)
		SLED	411..519	CDD:463469	105/107 (98%)
		SAM_Scm	645..715	CDD:188977	67/69 (97%)