Protein Alignment SNW1 and Bx42

DIOPT Version :10

• Sequence 1: NP_001305773.1
• Gene: SNW1 / 22938
• HGNCID: 16696
• Length: 571
• Species: Homo sapiens
• Sequence 2: NP_511093.2
• Gene: Bx42 / 31840
• FlyBaseID: FBgn0004856
• Length: 547
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 304/482 - (63%)
• Similarity: 364/482 - (75%)
• Gaps: 13/482 - (2%)

Human     1 MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFP 65
            |:|:|.||.||....|:.:..........:..:|||::...||||.||.|:|....|||||||||
  Fly     1 MSLSSLLPTPTNAIWDREDERRLVARGAPKIGALVSAKIAAPPYGQRKDWVPHTDADFGDGGAFP 65

Human    66 EIHVAQYPLDM---GRKKKMSNALAIQVDSEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNA 127
            |||||||||.:   |...|.|:|||:::|.:||:|||||||||..|||::||..:.|:|.||:..
  Fly    66 EIHVAQYPLGLGAPGNVGKKSDALAVRLDDKGKVKYDAIARQGHGKDKIVYSSISQLLPAEVLAE 130

Human   128 DDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGA 192
            |..:|||||||.:.|.||:||:||||..:||:.:|:|||.|.|..|||||||||||||..|||||
  Fly   131 DADELQRPDEETVMETTEETRLALEKLTNQKITSALPVRHAQKAGPAQYIRYTPSQQGDTFNSGA 195

Human   193 KQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNA 257
            |||||||||.|.||||||:|:||||||||||||||||:||||||:|||||:||||||||||||||
  Fly   196 KQRVIRMVEAQLDPMEPPKFRINKKIPRGPPSPPAPVLHSPSRKVTVKEQKEWKIPPCISNWKNA 260

Human   258 KGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEE 322
            |||||||||||||||||||.|||||.|||:||||||||||||||||.|:|:|:|:|||||||.|:
  Fly   261 KGYTIPLDKRLAADGRGLQQVHINEKFAKMAEALYIADRKAREAVEARSQLEKKLAQKEKEKKED 325

Human   323 KLREMAQKARERRAGIKTHVEKE-------DGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKL 380
            .||.|||:|||.|||::.....|       ..|.|||:::|.:|::|||.||||.||||:|||||
  Fly   326 MLRMMAQRAREERAGLRNPEAAEPSGSGATGSEVRERNDLRAERQRERQRDRNLQRAAPEKRSKL 390

Human   381 QRNENRDISEVIALGVPNPRTSN-EVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMA 444
            |:...|||||.||||:|.....| |..:||||||.:||||||:  |:||.|||||:.||....:.
  Fly   391 QKERERDISEQIALGLPAKSAGNGETLFDQRLFNTTKGMDSGY--GDDEAYNVYDKPWRDSNTLG 453

Human   445 QSIYRPSKNLDKDMYGDDLEARIKTNR 471
            ..||||||..|.|.||.||:|.:.|.|
  Fly   454 AHIYRPSKQADSDNYGGDLDAIVNTKR 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNW1	NP_001305773.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		14/44 (32%)
		Interaction with PPIL1. /evidence=ECO:0000269|PubMed:16595688	59..79		17/22 (77%)
		SNW	174..339		141/164 (86%)
		SKIP_SNW	178..334	CDD:460666	133/155 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..233		20/23 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	311..386		44/81 (54%)
Bx42	NP_511093.2	SKIP_SNW	181..337	CDD:460666	133/155 (86%)