Protein Alignment RAB18 and Rab8

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 206
• Identity: 79/206 - (38%)
• Similarity: 117/206 - (56%)
• Gaps: 32/206 - (15%)

Human    10 KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLHQQTANFFL 74
            |:|:||:|||||:.:|.||::|.|:....:|||:|||::||.:|..|.||.||
  Fly    10 KLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIW------------ 62

Human    75 KSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYC 139
                             ||||||||||:|.:|||||.|::||||:|:..:|..:.||:..:|...
  Fly    63 -----------------DTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENA 110

Human   140 TRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI-IQTP 202
            :. |:..||:|||.: .:.|:|.:..|.:.|.::.:.|:|.|||....|:.||..|...| .:|.
  Fly   111 SA-DVEKMLLGNKCELTDKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTE 174

Human   203 GLWESENQNKG 213
            ...|:.|..||
  Fly   175 KRMEANNPPKG 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	73/188 (39%)
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	74/191 (39%)