Protein Alignment RAB18 and Rab4

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_523777.1
• Gene: Rab4 / 36992
• FlyBaseID: FBgn0016701
• Length: 213
• Species: Drosophila melanogaster
• Alignment Length: 231
• Identity: 91/231 - (39%)
• Similarity: 121/231 - (52%)
• Gaps: 43/231 - (18%)

Human     1 MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTL 65
            |.|......|.||||.:|.|||.||..|.:..|..:.:.||||:|..:.::|.|...||.||
  Fly     1 MSETYDYLFKFLIIGSAGSGKSCLLHHFIESKFKDDSSHTIGVEFGSRIVNVGGKSVKLQIW--- 62

Human    66 HQQTANFFLKSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDN 130
                                      |||||||||::|.||||||.|.:||||.|.||:|..|.|
  Fly    63 --------------------------DTAGQERFRSVTRSYYRGAAGALLVYDATSRDSFNALTN 101

Human   131 WLNELETYCTRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEEL 194
            |||:..|..:.| ||.:|||||.| :|.|:|...|...||:::.::|:|.||||.:.|:.||.:.
  Fly   102 WLNDARTLASPN-IVILLVGNKKDLEEARDVTFLEASTFAQENELIFLETSAKTGENVEEAFLKC 165

Human   195 VEKI---IQTPGLWESENQNKGVKLSHREEGQGGGA 227
            .:.|   |:| |..:.|....|:        |.|||
  Fly   166 SKTILAKIET-GELDPERIGSGI--------QYGGA 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	79/189 (42%)
Rab4	NP_523777.1	Rab4	9..169	CDD:206696	79/189 (42%)