Protein Alignment RAB18 and Rab30

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 87/243 - (35%)
• Similarity: 125/243 - (51%)
• Gaps: 42/243 - (17%)

Human     3 EDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLHQ 67
            ||.....||:::|.:||||:.|:.|||...|.|...|||||||.:||:.|:|.|.||.||
  Fly     2 EDYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIW----- 61

Human    68 QTANFFLKSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWL 132
                                    |||||||||::|.||||.|..:|||||::.:.||..|.:||
  Fly    62 ------------------------DTAGQERFRSITQSYYRSAHALILVYDISCQPTFDCLPDWL 102

Human   133 NELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEK 197
            .|::.| ..:.::.:|||||.|:::||:....|.:||::|.|.|:|.|||..:.|:..|.|:..:
  Fly   103 REIQEY-ANSKVLKILVGNKTDRDDREIPTQIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAE 166

Human   198 IIQTPGLWESENQNKGVKLSHREEGQGGG------------ACGGYCS 233
            :|......:..:.........:.||...|            .|||..|
  Fly   167 LIGQARSKDGSSSAAAAAAQRQSEGSSIGLGSFSAKAAQSNCCGGLAS 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	77/188 (41%)
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	79/195 (41%)