Protein Alignment RAB18 and Rab21

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_001036321.2
• Gene: Rab21 / 3355163
• FlyBaseID: FBgn0039966
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 78/240 - (32%)
• Similarity: 118/240 - (49%)
• Gaps: 53/240 - (22%)

Human    10 KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISV-DGNKAKLAIWVTLHQQTANFF 73
            |.:::||..|||:||:||:.:|.|:.:..:|:...|..:.:|: ||.:|:|.||
  Fly    15 KAVLLGEGCVGKTSLVLRYMEDRFNAQHLSTLQASFVSRKMSLEDGRRAQLNIW----------- 68

Human    74 LKSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETY 138
                              ||||||||..|.|.||||:.|.:||||:|.||:|.|:.:|:.||. .
  Fly    69 ------------------DTAGQERFHALGPIYYRGSDGALLVYDITDRDSFQKVKSWVRELR-Q 114

Human   139 CTRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKI---- 198
            ....:|..::||||.| :|.|.|..:|.|::||.....::|.|||..:||...||.|.:.:
  Fly   115 MRGTEIALIIVGNKTDLEEQRAVTHDEALQYARTVGAQYVETSAKENEGVAELFELLTQLMLEQL 179

Human   199 -----------IQTPGLWESENQNKGVKLSHREEGQGGG---ACG 229
                       :|.|   :::|.|........:.|...|   .||
  Fly   180 SQRQPDASPLRLQNP---DTDNLNNSDDSEAPDPGDPAGQRSCCG 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	70/189 (37%)
Rab21	NP_001036321.2	Rab21	14..176	CDD:133323	70/190 (37%)