Protein Alignment RAB18 and Rab10

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 87/228 - (38%)
• Similarity: 128/228 - (56%)
• Gaps: 35/228 - (15%)

Human     4 DVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLHQQ 68
            |:|  .|:|:||:|||||:.:|.||:||.|.....:|||:|||:||:.:.|.|.||.||
  Fly     7 DLL--FKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIW------ 63

Human    69 TANFFLKSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLN 133
                                   ||||||||.|:|.||||||.|::||||:|...:|..:..||.
  Fly    64 -----------------------DTAGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLR 105

Human   134 ELETYCTRNDIVNMLVGNKID-KENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEK 197
            .::.: ...|:..|::|||.| .:.|.|::..|...||:|.:.|:|.|||:...::.||.||.|.
  Fly   106 NIDEH-ANEDVEKMILGNKCDMTDKRVVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEA 169

Human   198 II-QTPGLWESENQNKG-VKLSHREEGQGGGAC 228
            |: :|.|...:|||.:. :...::|:..|...|
  Fly   170 ILDKTSGRESAENQERVIIDRRNQEKAPGYSKC 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	76/189 (40%)
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	79/197 (40%)