Protein Alignment RAB18 and Rab35

DIOPT Version :10

• Sequence 1: NP_001243339.1
• Gene: RAB18 / 22931
• HGNCID: 14244
• Length: 235
• Species: Homo sapiens
• Sequence 2: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 88/226 - (38%)
• Similarity: 123/226 - (54%)
• Gaps: 43/226 - (19%)

Human    10 KILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWVTLHQQTANFFL 74
            |:||||:|||||||||:||:||||......|||||||::|:.::|.:.||.||
  Fly    10 KLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIW------------ 62

Human    75 KSQIGNSPILKWAMWQYDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYC 139
                             ||||||||||:|.:||||..|||:|||||..::|..:..||.|::..|
  Fly    63 -----------------DTAGQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNC 110

Human   140 TRNDIV-NMLVGNKIDKENREVDRNE-GLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQ-- 200
               |:| .:|||||.|..:|:|...| ..:||::..:...|.|||....|:..|..:..:::.
  Fly   111 ---DVVKKVLVGNKNDDPDRKVVITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHK 172

Human   201 ---TPGLWESENQNKGVKLSHREEGQGGGAC 228
               :|    :|.|...:.|....:|..||.|
  Fly   173 LRTSP----NEQQKDTLHLKPNPKGSKGGKC 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB18	NP_001243339.1	Rab18	9..198	CDD:206656	80/189 (42%)
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	88/226 (39%)