Protein Alignment SEPHS1 and Sps1

DIOPT Version :10

• Sequence 1: NP_036379.2
• Gene: SEPHS1 / 22929
• HGNCID: 19685
• Length: 392
• Species: Homo sapiens
• Sequence 2: NP_725374.1
• Gene: Sps1 / 36587
• FlyBaseID: FBgn0261270
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 269/374 - (71%)
• Similarity: 320/374 - (85%)
• Gaps: 5/374 - (1%)

Human     4 RESFNPESYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDE--QFLGAVMPRLGI 66
            |..|:|.:::||.|||||||.:|||.|||||||||.||:.:||:::..:|:  |||...:||:||
  Fly    24 RRPFDPTAHDLDASFRLTRFADLKGRGCKVPQDVLSKLVSALQQDYSAQDQEPQFLNVAIPRIGI 88

Human    67 GMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNK 131
            |:|..|||||||||.||||||:.|||||||||||:||||||||||||||||:||||||||.||.|
  Fly    89 GLDCSVIPLRHGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLLAVSTK 153

Human   132 MTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDV 196
            ||::|||.|:|||::||||:|.||||:|||||:|:|||..:||||:|:|||||:|:|||||.|||
  Fly   154 MTEKERDVVIPLIMRGFKDSALEAGTTVTGGQSVVNPWCTIGGVASTICQPNEYIVPDNAVVGDV 218

Human   197 LVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAH 261
            |||||||||||||..|||:|.||:||:|||||::|||..||..||.:||||||.||.|||.:|||
  Fly   219 LVLTKPLGTQVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMNSMARLNRVAARLMHKYNAH 283

Human   262 AATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLI 326
            .||||||||:|||||.||..|:.:||||||||||:||||||:|||||||.|:.|...||||||||
  Fly   284 GATDITGFGLLGHAQTLAAHQKKDVSFVIHNLPVIAKMAAVAKACGNMFQLLQGHSAETSGGLLI 348

Human   327 CLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEV 375
            ||||||||.:|.:|:..   ||:||||||||||||:|||||||||:|||
  Fly   349 CLPREQAAAYCKDIEKQ---EGYQAWIIGIVEKGNKTARIIDKPRVIEV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SEPHS1	NP_036379.2	selD	19..333	CDD:273100	231/315 (73%)
Sps1	NP_725374.1	SelD	40..376	CDD:100031	243/338 (72%)