Protein Alignment MAPRE3 and CG32371

DIOPT Version :10

• Sequence 1: NP_036458.2
• Gene: MAPRE3 / 22924
• HGNCID: 6892
• Length: 281
• Species: Homo sapiens
• Sequence 2: NP_729295.1
• Gene: CG32371 / 317999
• FlyBaseID: FBgn0052371
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 112/291 - (38%)
• Similarity: 164/291 - (56%)
• Gaps: 43/291 - (14%)

Human     3 VNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKL 67
            |||..|:..|.|.||.:||:|||::|...:.|:|:||:||||||.||:||...:.:::|||:..:
  Fly    10 VNVRYTNKLSSNSSRAEMLSWVNNTLKSQFFKVEELCTGAAYCQLMDILFARSIPMQRVKFRTNV 74

Human    68 EHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQG 132
            |:|||.|||:||..|.|..||||||:::||||::||||||:|||:|||||||:.::|:|::||.|
  Fly    75 EYEYIQNFKLLQGCFNKFVVDKIIPIDRLVKGRYQDNFEFLQWFRKFFDANYESREYDPVIARNG 139

Human   133 Q--DVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNP--PSARN 193
            .  .:..||...     |.:|.:..:.|| |.||...:.||. |.:......:.:.|.  .:...
  Fly   140 AMLGLGSPPMEA-----KLRKSVNKSNPQ-TKPTEESSAQTD-RATTEPKNQVYKSNSENKTIEE 197

Human   194 GGHETDAQILELNQQLVD--LKLT-----------------------------VDGLEKERDFYF 227
            ...:||..|.|...|:.:  .|.|                             |..:::||:||.
  Fly   198 ASAQTDLAITEPENQVHESQTKTTEKASAQTEKATTEPDSEGSIEELRNYCKYVSRMKQERNFYL 262

Human   228 SKLRDIELICQEHESENSPVI-SGIIGILYA 257
            ||||.|:.|||::.|....|| ..|..|:|:
  Fly   263 SKLRAIDHICQKYNSGRDRVILEKITKIIYS 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPRE3	NP_036458.2	BIM1	16..279	CDD:227542	106/278 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..181		8/23 (35%)
		DCTN1-binding	217..281		18/42 (43%)
		APC-binding	217..260		18/42 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..281
CG32371	NP_729295.1	BIM1	23..>269	CDD:227542	96/252 (38%)
		EB1	254..293	CDD:460870	17/38 (45%)