Protein Alignment DHX30 and bgcn

DIOPT Version :9

• Sequence 1: XP_011531792.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Sequence 2: NP_523832.2
• Gene: bgcn / 47873
• FlyBaseID: FBgn0004581
• Length: 1215
• Species: Drosophila melanogaster
• Alignment Length: 1027
• Identity: 225/1027 - (21%)
• Similarity: 365/1027 - (35%)
• Gaps: 320/1027 - (31%)

Human   400 MYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGK----- 459
            :|.||..|   ..|:.|||.:..|.     |.|.|:        |..|.|:|..:...|.
  Fly    15 LYFLAGRR---CCQQFPCTFRTSEH-----EAFANN--------ARSLGLRSQVVHVNGNSCVKV 63

Human   460 -----------------DSGPLSDPITGKPYVPLLEAEEVRLSQSL--------------LELWR 493
                             .||...:..|......|:..|::.|...|              |.|..
  Fly    64 YKQACRHYLEEPKTLVLSSGATLNMFTLLSRKSLMGKEDLELYADLVSMKANASDLPSLHLPLPA 128

Human   494 RRGP---VWQEAPQLPV------DPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTE 549
            .|.|   .|.|| ||..      ....|.||.::....|:|.:......|:..:|.::|:    :
  Fly   129 IRPPNLRFWTEA-QLNFLTAFLGHSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILD----D 188

Human   550 GRGARCNVII--TQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILL 612
            .|..:.||.|  .:.:.|.|...:||.::..|..|...||.|:...| ..|....:::.|....|
  Fly   189 CRNKKSNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFS-AVSSSTFIIYSTAQYFL 252

Human   613 RKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFG-- 675
            |.|.|. ....:||::|::||..|..||.||..::.....:..||:||:|..|:.::|:.:||
  Fly   253 RSLTSQ-QFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFFGEG 316

Human   676 -GCPVIKVP-------------------------------------------------------- 683
             ...:||.|
  Fly   317 LQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYGELG 381

Human   684 ------GFMYPVK--------------------------------------EHYLEDIL------ 698
                  .|:|.|.                                      :.|:.|:.
  Fly   382 TDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQNAIS 446

Human   699 --AKLGKHQ---YLHRHRHH----ESEDECALDLDLVTDLVLHIDARGE-------PGGILCFLP 747
              |..|.|:   .|:.:..|    :|.....:|.||:.|::..:..:.|       ||.||..||
  Fly   447 LAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILIILP 511

Human   748 GWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIF----------QQPPVGVR----KI 798
            .:..|.             :..|:||. |.....:.:.:||          .|..|...    |:
  Fly   512 TYYHIV-------------KLNYMILS-HCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVKV 562

Human   799 VLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCL---ETVWVSRANVIQR----RGRAGR 856
            ||||:|.|:........:.:|:.......||   ..||.   ...||::..:::|    :...|.
  Fly   563 VLATDIIESLCLKVPFKYQIDTACRLNNVYD---TTSCSGDDRFEWVAKDALLRRELILQPNKGD 624

Human   857 CQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDE 921
            .|   .:.|..:...|::.....|.:....|:.:.|..|:..|.....|:|...:..|.:..|..
  Fly   625 VQ---CFRLISKEAYEELSETSQPSLQTMQLDKICLAVKLLSPNTIISEYLGITISPPPLINVHH 686

Human   922 AVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCL-TRD----P 981
            ||..|::|.|||..|.:|.||.||..|....:|.:.::...:.|||.|:|.:||.| |.|    |
  Fly   687 AVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIP 751

Human   982 FSSSLQN---------RAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSREN---YLE 1034
            |:..:.|         :..:.|.:..||.:..|||..|||.   ::|   ||:|.....   ||:
  Fly   752 FTEDIDNLWDRFTIYIQNSIKKERTYLSDNQFSDHFIFVRL---YKE---WQNRMHNRTPPLYLK 810

Human  1035 ENLLYAPSLRFIHGLIKQFS-------ENIYEAFLV---GKPSDCTLASAQCNEYSEEEELVKGV 1089
            :...:     .::||::|.:       .::..|.|:   ||.|...|....||.:     :||..
  Fly   811 DEYEF-----MLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWH-----MVKAA 865

Human  1090 LMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINRE--------ATRLRSRWLT 1146
            |..|:|||:..|...|.:.:..|          |||:.:|.:|:.|:        |...|:.|:
  Fly   866 LTGGMYPNIYAVDTRKSSLKSAF----------SGNVSMHPNTVLRDFLEPLNISAQSFRTPWI- 919

Human  1147 YFMAVKSNGSVFVRDSSQVHPLAVLL------------------LTDGDVHI 1180
                |.:.....:..::.|.||||.:                  |||.:|::
  Fly   920 ----VCNRQKSHIVYATLVVPLAVAMFSGHPRIRLSPICDSEMSLTDRNVNV 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX30	XP_011531792.1	HrpA	494..>1143	CDD:224557	188/840 (22%)
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	1/31 (3%)
		ANK	407..>460	CDD:238125	5/52 (10%)
		Ank_2	413..>460	CDD:289560	5/46 (11%)
		HrpA	<484..973	CDD:224557	128/535 (24%)
		HA2	694..763	CDD:214852	25/68 (37%)
		OB_NTP_bind	823..945	CDD:285018	34/141 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810