Protein Alignment DHX30 and Dhx15

DIOPT Version :10

• Sequence 1: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Sequence 2: NP_610269.1
• Gene: Dhx15 / 35654
• FlyBaseID: FBgn0033160
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 726
• Identity: 215/726 - (29%)
• Similarity: 356/726 - (49%)
• Gaps: 106/726 - (14%)

Human   463 PLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVIS 527
            |..:|:|..||           ||....|:::|       ..|||..::...:..:..|..:|:.
  Fly    48 PTMNPLTNTPY-----------SQRYQNLYKKR-------IALPVFEYQADFMRLLSLHQCIVLV 94

Human   528 GDTGCGKTTRIPQLLLERYVTEGR-GARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVR 591
            |:||.||||:|||..::..|::|| |..|    |||||::|:|||||||.|:...|...||:.:|
  Fly    95 GETGSGKTTQIPQWCVDFAVSKGRKGVSC----TQPRRVAAMSVAQRVSEEMDVKLGEEVGYSIR 155

Human   592 LESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPAL 656
            .|....:: ..|.:.|.|:|||:..|:|.|:....:::||.|||.:.||.|:.:||.:.|....|
  Fly   156 FEDCSTAK-TLLKYMTDGMLLREAMSDPMLDQYQVILLDEAHERTLATDILMGVLKEVIRQRSDL 219

Human   657 RLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECAL 721
            :||:||||.|..:|.:||...|::||||..:||:..|..:     .:..||          |.|:
  Fly   220 KLVVMSATLDAGKFQQYFDNAPLMKVPGRTHPVEIFYTPE-----PERDYL----------EAAI 269

Human   722 DLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQ---EALGMHESKYLILPVHSNIPMMD 783
            .    |.:.:|:....| |.||.||.|.:||:...:|::   :.||....:...:|::|.:|...
  Fly   270 R----TVIQIHMCEEIE-GDILMFLTGQEEIEEACKRIKREIDNLGSEIGELKCIPLYSTLPPNL 329

Human   784 QKAIFQQPP-------VGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVW 841
            |:.||:..|       :| ||:|::|||||||:||:.:|.|:|.|..|::.|:.:.:|..|....
  Fly   330 QQRIFEPAPPPNANGAIG-RKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSP 393

Human   842 VSRANVIQRRGRAGRCQSGFAYHLFPRSRLE-KMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAV 904
            :|:|:..||.|||||.:.|..:.|:.....: :|.....|||||:.|..:||| .|:.:.:....
  Fly   394 ISKASAQQRSGRAGRTRPGKCFRLYTEKAFKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHF 458

Human   905 EFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHP 969
            :|:    |.|..:.:..|:.||..:..||....||.||..::....||:|||.::.:....|.:.
  Fly   459 DFM----DPPAPETLMRALELLNYLAALDDDGNLTDLGAVMSEFPLDPQLAKMLIASCQHNCSNE 519

Human   970 LLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYL 1033
            :|.:.:.|: ...|....:.:...|:.|...:|..| |||..:.....:::      .|...|:.
  Fly   520 ILSITAMLSVPQCFVRPNEAKKAADEAKMRFAHIDG-DHLTLLNVYHAFKQ------SSEDPNWC 577

Human  1034 EENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELV--KGVLMAGLYP 1096
            .||.:...||:....:.:|.: .|.:.|.:.:.|         .|::.::..|  :..|:.|.:
  Fly   578 YENFINFRSLKSADNVRQQLA-RIMDRFNLRRTS---------TEFTSKDYYVNIRKALVQGFF- 631

Human  1097 NLIQVRQGKVTRQGKF---KPNSVTYRTKSGNILLHKSTINREATRLRSRWLTY--FMAVKSNGS 1156
              :||  ..:.|.|.:   |.|.        |:.||.||    ....:..|:.|  |:....|
  Fly   632 --MQV--AHLERTGYYLTIKDNQ--------NVQLHPST----CLDHKPDWVIYNEFVLTTKN-- 678

Human  1157 VFVRDSSQVHP 1167
             ::|..:.|.|
  Fly   679 -YIRTVTDVKP 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	175/545 (32%)
		OB_NTP_bind	1086..1173	CDD:400182	21/89 (24%)
Dhx15	NP_610269.1	HrpA	71..>691	CDD:441249	206/685 (30%)