Protein Alignment DHX30 and Rhau

DIOPT Version :10

• Sequence 1: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Sequence 2: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Alignment Length: 963
• Identity: 309/963 - (32%)
• Similarity: 505/963 - (52%)
• Gaps: 136/963 - (14%)

Human   384 KSLGLVDRNNEPLTHAMYNLA--SLRELGETQ-------RRPCTIQVPEPILRKIETFLNHYP-- 437
            |.:||..|          |||  ..::.||..       |..|.:..|..:|.:::..:..|.
  Fly    24 KDIGLYYR----------NLARQQKKDRGENAESKEPQIRLGCNVSAPSGVLERVKELMEDYSRA 78

Human   438 -----VESSWIAPELRLQSDDILPLG--------KDSGPLSDPITGKPYVPLLEAEEVRLSQSLL 489
                 |:...:..:.:.|...:|.:.        |:.....|.:..|    |.|..::.|.|..|
  Fly    79 PSRQNVDDKNVDAKFQQQFRHLLSVNFEEFVAETKERNADLDWVNPK----LDERLQLELGQRQL 139

Human   490 E------LWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVT 548
            |      |..|:        :||...:.|.|:.|:.::.|::|.|.|||||||::||:||:..::
  Fly   140 EENAKKRLEARK--------KLPTMKYADDIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAIS 196

Human   549 EGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLR 613
            .|..:.|.:|.||||||||:::|:.||:|...||..:||:|:||||:......::.:||.|:||:
  Fly   197 RGCASSCRIICTQPRRISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQ 261

Human   614 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCP 678
            :|||:|.:..:|.:|:||:|||.|.||.|:.|||.:....|.|:::|||||...:.|..||..||
  Fly   262 QLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCP 326

Human   679 VIKVPGFMYPVKEHYLEDILAKLG--------------------KHQ-----YLHRHRH-HES-- 715
            :.::.|.|:|||..||||:|:|..                    ||:     ||.|.|: ::|
  Fly   327 MFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRV 391

Human   716 -------EDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIK---GVQQRLQEALGMHESKY 770
                   |.|...|:|.:.|||.:|......|.||.||||:.:|.   .:..:.:.:.|.....:
  Fly   392 LDKLRLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDH 456

Human   771 L-ILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKV 834
            : :.|:||.:...:|:|:|::||.|.||::::|.|||||:||:|:|:|::||..|...||::|.:
  Fly   457 MAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNI 521

Human   835 SCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAK-IHM 898
            ..|:.|||::||..||||||||.:.|..|:||.|:|.::|.....|||||:.||:::|..| :|:
  Fly   522 QSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHI 586

Human   899 PEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAI 963
            .:  ...||...:::||.:|:...|.||:.|..|||...||.||..||.:..||::.|.|:::|:
  Fly   587 DD--PYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSAL 649

Human   964 FRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS 1027
            |.||.|:....:.|: :.||.|.|...:.||::|..::.:..||||.....:..:        |.
  Fly   650 FCCLDPITSAAAALSFKSPFYSPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAY--------RD 706

Human  1028 SRENYLE-----ENLLYAPSLRFIHGLIKQFSENIYE-AFLVGKPSDCTLASAQCNEYSEEEELV 1086
            ||.::.|     :|.|.:.:|:.:..:..||||.:|. .||..  |:|  ..|..|:.||:..|:
  Fly   707 SRYSHAERDFCYKNFLSSMTLQQLERMKNQFSELLYNYKFLAS--SNC--KDAASNKNSEKIPLL 767

Human  1087 KGVLMAGLYPNLIQVRQGKVTRQGKFKPNSV-TYRTKSG-NILLHKSTINREATRLRSRWLTYFM 1149
            :.::.||||||:..:|:   :||.|.:..:: |..|..| .:..|.|::|...:...|.:..||.
  Fly   768 RAIIGAGLYPNMAHLRK---SRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQ 829

Human  1150 AVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRR 1214
            ..||. .:|:.||:.|.|:|:::..||   :.....:.|..|..:.....:.:..|..::.:||.
  Fly   830 RQKST-DLFLLDSTMVFPMALIIFGDG---VEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRS 890

Human  1215 ALGRMVERSLRSELAALPPSVQEEHG---QLLALLAELLRGPCGSFDVRKTAD 1264
            .|.:::.:.      ||.|:..||:|   ||:..:..||     |.|.|...|
  Fly   891 NLEKLLLKK------ALYPAPIEENGYEKQLIKAIELLL-----SLDERLGED 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	212/572 (37%)
		OB_NTP_bind	1086..1173	CDD:400182	27/88 (31%)
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	197/505 (39%)
		OB_NTP_bind	767..856	CDD:400182	29/95 (31%)