Protein Alignment DHX30 and ath

DIOPT Version :10

• Sequence 1: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Sequence 2: NP_609356.2
• Gene: ath / 34357
• FlyBaseID: FBgn0032194
• Length: 694
• Species: Drosophila melanogaster
• Alignment Length: 732
• Identity: 203/732 - (27%)
• Similarity: 338/732 - (46%)
• Gaps: 145/732 - (19%)

Human   475 PLLEAE----EVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKT 535
            |:||.:    :::.:.:.:.|..:|..:.|:...|||...|..||..:|.:..|:|..:||.|||
  Fly    34 PILEKKPHVAQIKQTIAPILLTSKRTSIEQQQKSLPVFNCRHRILKELEANDTVLIMSETGSGKT 98

Human   536 TRIPQ-LLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSR 599
            |:||| |||..|...|.     :.||||||::|::||:||:.||..::...||:.||.|. ..||
  Fly    99 TQIPQFLLLAGYAKNGM-----IGITQPRRVAAITVARRVAQELNGTIGDTVGYTVRFED-VTSR 157

Human   600 GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLN-----PALRLV 659
            ...:.|.|.|:|||:...:..|...|.:|:||.|||.||.|.|..::|..|:..     ..|::|
  Fly   158 ATKIRFLTDGVLLRESIKDRLLLKYSVIILDEAHERTVNADLLFGIVKDAQKERRKQKLANLKVV 222

Human   660 LMSATGDNERFSRYFGGCPVIKVPGFMYPVK--------EHYLEDILAKLGKHQYLHRHR----H 712
            :.|||.|.:.|..|| .|..:.:.|..|||:        |.|:..:|..|     .|.||    :
  Fly   223 VTSATMDIDHFGNYF-NCKGMYLEGRTYPVRVMHTKEEHEDYIHTVLVTL-----FHIHRTTPKN 281

Human   713 HESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQ-----EALGMHESKYLI 772
            |:                           :|.||.|.:||:.:.|:::     :..|..:.:  :
  Fly   282 HD---------------------------VLIFLTGQEEIESLAQQIRQLAKIDTTGTTDLR--V 317

Human   773 LPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCL 837
            ..:::.:....|...|...|..|||::||||||||||||..|..|:|.|..||:.::....:..|
  Fly   318 FTLYAQLSQGKQLECFVPTPANVRKVILATNIAETSITIPGIRCVIDCGFVKEKSFNTVDGLDVL 382

Human   838 ETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKT 902
            ::|.:|:|...||.|||||...|..|..:.::.::.......||||||...::|||
  Fly   383 KSVRISKAQAWQRAGRAGRDADGTCYRAYTKAEMDSFADATQPEILRTNPTSMVLQ--------- 438

Human   903 AVEFLSKAVDSPNIKAVD--------EAVILLQEIGVLDQRE--YLTTLGQRLAHISTDPRLAKA 957
               .|:..:|..|...:|        .|...|..:|.:...:  |:|.||:::.....||:.:|.
  Fly   439 ---LLALDIDCNNFDFLDPPLEDGLRSAYKSLDALGAIKTGDDSYITPLGRQMVQYPLDPKYSKL 500

Human   958 IVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSH----DSGSDHLAFVRAVAGW- 1017
            ::.|:.|.|:..:|.:||.|:.|....|...:.|:    |.|:|    ....|||..:....|:
  Fly   501 LLTASSFGCMEEILSLVSVLSSDHVFVSNSEKNEM----AALAHAKFQSKHGDHLTLLNVFNGFL 561

Human  1018 --EEVLRWQDRSSRENYLE-ENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEY 1079
              |:...|    ..:|||. .:|.||   |.:...:::.||:::.|.                ..
  Fly   562 KSEKPKMW----CHDNYLNLRSLTYA---RNVRRQLREISEHLHLAL----------------NS 603

Human  1080 SEEEELVKGVLMAGLYPNLIQVRQ--------GKVTRQ--------GKFKPNSVTYRTKSGNILL 1128
            |::.|::|..::.|.:.|:..:::        |.:..:        ||:||:.:.:.    .|:.
  Fly   604 SDDIEMLKKCILNGFFENIAVLQRDGFYITASGNIRSKIHPSSVLHGKYKPSYILFT----EIVQ 664

Human  1129 HKSTINREATRLRSRWL 1145
            .:.|..|:.|.:...|:
  Fly   665 TEQTFLRQVTEISIEWI 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	173/571 (30%)
		OB_NTP_bind	1086..1173	CDD:400182	13/76 (17%)
ath	NP_609356.2	HrpA	67..>686	CDD:441249	197/699 (28%)