Protein Alignment DHX30 and CG32533

DIOPT Version :10

• Sequence 1: XP_047303683.1
• Gene: DHX30 / 22907
• HGNCID: 16716
• Length: 1265
• Species: Homo sapiens
• Sequence 2: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Alignment Length: 795
• Identity: 229/795 - (28%)
• Similarity: 385/795 - (48%)
• Gaps: 95/795 - (11%)

Human   332 TAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRR--KAEAENKAAALACKKLKSLGLVDRNNE 394
            |..||::|..:..|.:|..|         ..||.|:  ::..||:|     ...|.:|..:
  Fly    18 TQINLIEFSFLDHKAELVGL---------LQAKSRQVGRSLVENEA-----DFWKFVGKYE---- 64

Human   395 PLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGK 459
                     |.:|..|:....|   ::.|..|..::.:  |   .|..:|  |||.:|::|...:
  Fly    65 ---------AMMRSTGQPVLPP---RLAEAELSSMQPY--H---RSKHLA--LRLDADELLQEAR 110

Human   460 DSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVV 524
            |............|:...:.|:.:..:.|.:..|          .||:...|..:..|::...||
  Fly   111 DQMQSQFRHILLVYLDFRQTEKFQRIRKLRQTQR----------NLPIARFRKDLREALDTSRVV 165

Human   525 VISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQ 589
            :::|||||||:|::||.|.:      .|.| ::..|||||::.||:.:||:|||.......|.||
  Fly   166 IVAGDTGCGKSTQVPQYLYD------FGYR-SIACTQPRRLACVSLCKRVAHELLDDYGSRVAFQ 223

Human   590 VRLESKPPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNP 654
            :|.| :..::...:||.|.|:|||:|....:|:....:|:||:|||::..||||.:.|.|.|..|
  Fly   224 IRFE-RSRTKLTNILFITEGLLLRQLAVAANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARP 287

Human   655 ALRLVLMSATGDNERFSRYFG--GCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESED 717
            .|:|:|||||.:.|.|..|||  |..:::|||.::|:|..||.....:|...|...:.......|
  Fly   288 QLKLILMSATINVELFHGYFGEEGARLVQVPGRLFPIKLRYLPPPALELKAGQATSKRSQRNRID 352

Human   718 ECALDLDLVTDLVLHIDAR---GEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNI 779
            ....     ..::..||.:   .|.|.:|.|:.|..||:.|.:.:.| ....::.:|:||:||..
  Fly   353 PAPF-----VQVLSLIDQQYPTSERGDVLIFVSGVNEIESVVEAVHE-YATEQTHWLVLPLHSGQ 411

Human   780 PMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSR 844
            .:.||..:|...|.|:||.:::|||||||:|::.:..|||||..||..:|...|...|:..|||:
  Fly   412 AIADQSKVFDYAPEGMRKCIVSTNIAETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSK 476

Human   845 ANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQ-AKIHMPEKTAVEFLS 908
            ::..||:|||||...|..:.|:...:......:..|||.|.||:.::|| ..:.:|:..|..|
  Fly   477 SSADQRKGRAGRTGPGVCFRLYTAEQYNAFEAYPTPEIYRVPLDTMLLQMVSMGLPDVRAFPF-- 539

Human   909 KAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVV 973
              :::|..:.:::.::.|::...|...|.:|.||:.||::..:..:.|.:::.::|..:..||.:
  Fly   540 --IEAPETERIEQTILALKQHCALSVEEKITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLLTL 602

Human   974 VSCLTRDPFSSSLQNRAEVD----KVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRS---SREN 1031
            .:.|:   ..:.|.|||..|    :.:..|..|.| |....||....|.::...:|.:   .|..
  Fly   603 AAMLS---VQNPLTNRAHTDQRCVRERESLESDHG-DLFTLVRLYNVWVQLKMRRDGTRQWCRRL 663

Human  1032 YLEENLLYAPSLRFIHGLIKQFSENIYEA--FLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGL 1094
            .:||...|.     :..|.:|| :.|.|:  .:|...||..|.||:......|...:|.:.....
  Fly   664 GIEEQRFYE-----VTKLRQQF-QRILESCGMVVASDSDSQLTSAERATRHGELRQLKAMKRRQR 722

Human  1095 YPNLIQVRQGKVTRQ 1109
            :.   |.||.|:.:|
  Fly   723 FE---QPRQRKLLKQ 734

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX30	XP_047303683.1	HrpA	497..>1029	CDD:441249	173/544 (32%)
		OB_NTP_bind	1086..1173	CDD:400182	6/24 (25%)
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	164/494 (33%)
		OB_NTP_bind	792..897	CDD:400182