Protein Alignment NLGN1 and alpha-Est1

DIOPT Version :10

• Sequence 1: NP_001352852.1
• Gene: NLGN1 / 22871
• HGNCID: 14291
• Length: 843
• Species: Homo sapiens
• Sequence 2: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Alignment Length: 156
• Identity: 40/156 - (25%)
• Similarity: 60/156 - (38%)
• Gaps: 44/156 - (28%)

Human   267 PPENGLDKARG---------------LKKDAPTSPASVASSSSTPSSKTKDLG---HNDKSS--T 311
            ||.   |.:||               |:|   ||.|...:|||..|.:.|...   :|.|.|  .
  Fly   158 PPR---DSSRGPAKCGCGFHKIVKSPLRK---TSSAGSDTSSSGQSFRNKIFKRPMNNRKISMQK 216

Human   312 PGLKSNTPTPRNDAPTPGTSTTPGLRSMPGKPPGMDPI---ASALRTPITLTSSYPAPFAMMSHH 373
            |.:..:..:|...:.:.|.:||       .:....|.|   :|.:...|||.|       ..|:.
  Fly   217 PEIVIDEISPNRISISAGGNTT-------FRRSSDDCIRRSSSEIIGGITLPS-------QSSND 267

Human   374 EMNGSLTSPSAYAGLHNIPSQMSAAA 399
            :..||..|.|: |.||...::|:..|
  Fly   268 KRRGSGMSNSS-ASLHIHETRMTFEA 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NLGN1	NP_001352852.1	COesterase	52..626	CDD:395084	40/156 (26%)
alpha-Est1	NP_524269.3	COesterase	31..555	CDD:395084	40/156 (26%)