Protein Alignment CEP162 and CG42699

DIOPT Version :9

• Sequence 1: NP_055710.2
• Gene: CEP162 / 22832
• HGNCID: 21107
• Length: 1403
• Species: Homo sapiens
• Sequence 2: NP_572263.2
• Gene: CG42699 / 31507
• FlyBaseID: FBgn0261610
• Length: 897
• Species: Drosophila melanogaster
• Alignment Length: 975
• Identity: 187/975 - (19%)
• Similarity: 368/975 - (37%)
• Gaps: 272/975 - (27%)

Human   472 QLSSEEEGAV-----MGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKK 531
            :|..|.|..:     :|..|| |...|.||    .|...|.....:.|.|..|||       :..
  Fly    66 ELLQEAERLIQQQLRLGGIVP-KLDASGPP----APTKTLGEEAATGGDGSSSSP-------QSS 118

Human   532 TSEDI-IKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCI 595
            ....| :.::....|..|..|...:.::....::|.             |..|.|.:||.    :
  Fly   119 PHSSIRLNTRYTHRIEHSPAPLAPKTVAVNGRVRPR-------------SGSKSSASPTS----V 166

Human   596 QFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEK 660
            |...:|...||            .....|....|..:.|:    .:.|:.::||....:.|.|.:
  Fly   167 QTPLESSNGCG------------FAAFVDNLPSASVISEE----STPKDMDMENHTAAMAKLQLQ 215

Human   661 ELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENE 725
            :|    |||      ....|:|                        .:||.|.|.        :.
  Fly   216 QL----QDN------TDDDEDT------------------------MEEITEAEV--------DA 238

Human   726 RLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAE 790
            .::::.:|..::.:...||.||.....:.:.:   :.:......|:....|.|.|      :::.
  Fly   239 PIFSRAEDTGKEVRSPPERQFKSQGRSYIQPS---QPIRPMASYSEKAVGSSPKR------MVST 294

Human   791 LRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEI 855
            |       .|.:|.|......:.||:::.|::   :::.||     |.|:|..:::..::..|..
  Fly   295 L-------TSPIEQIASSVSREHALKLEIEQL---QERLKD-----TEERLASVRLQSDSLSQTQ 344

Human   856 SRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKD------- 913
            ..|::......|..|:|..|...|   ||....|:.|::..:.:.|. :::.:..|:|
  Fly   345 RALREHNSRLQEESEMLKLDVQHL---NECANVLRSELQAARRDRGE-ALQMQRSLRDELEEANQ 405

Human   914 --------KAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAG-----DTVDKNTVEFM 965
                    |..|::.||||:||.:|||.||.|::|:|:.|||:|:.::|     |..:.|:.:.:
  Fly   406 ERRRTGEGKEKDSRVIQDLQRQCREMERILMRKHPDSVSALIVASKSSGMCPLNDQENVNSRKLL 470

Human   966 EKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE------QLLACKLNQHDSPRI 1024
            |:||.:||:|.:.:|..|::.|..::.:|..::.:||..:...|      |.:..|||:....::
  Fly   471 EQRIAQLESDAKEQDRKAQQILANVQARFNSVQAKYETHIADLETQVLSLQEINTKLNEQIESQV 535

Human  1025 KALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVR 1089
            :.|:              |.::...|  ::.|   :..:.:..:||..|:...|.  |.:|..|.
  Fly   536 RTLD--------------RYMQKRAD--RYYN---NCTQTEPLEEDDVSVGGGVN--HGRATPVS 579

Human  1090 LNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMS---------AKRAKKDVLHSSKG 1145
            .|                        .|....|.:.|..:.|         |...::..||.:.|
  Fly   580 SN------------------------TMGTQTQAANGTRDHSTNTIGCPSPALVCQQQHLHQAHG 620

Human  1146 N---------------ANSFPGTL-------------------DSKLYQPHTFTDSHVSEVLQEN 1176
            :               |||.|.|.                   .|||  |.:.:||.:|.:....
  Fly   621 HLHPHAPSASSSTSSTANSTPNTSRPNSKQSGGQRRSPLVTAGPSKL--PISQSDSTLSLLSHGG 683

Human  1177 YRLKNELEGLISEKN---ELKMKSEAV------MNQFENSMRRVKEDTAAHIASLKASHQREIEK 1232
            ...|.|.:.|.|.::   :|.:|::|:      :::.:.::|:::.|.....:..:...:.::..
  Fly   684 GGSKEEAQLLSSVRSMRVDLAIKNKAMQRLTRELDECKKTIRKLQRDKEGSGSGSQTGSKLDLRS 748

Human  1233 LLCQNAVENSSSKVAELNR-----KIATQEVLIRHFQSQVNELQSKQESLVVSEVRE-------- 1284
            .....|::...|...:.:.     ..||:...::..|::...|::..::|....:::
  Fly   749 QASGGAMQQRRSSGYDHHHHSDHIPAATESQALKEAQNKYRLLEADYKTLHDKRLQDLKTLQSAH 813

Human  1285 -----------EILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQ 1338
                       .|||:.:.:..|.|...|....|  ..:..|:.|:..:|.||::||:.|..:::
  Fly   814 ERELASCNETVRILQQRLNEREEALTTQKRRKVP--VDYYALKAKVSLLERRHSEREERLHMLVE 876

Human  1339  1338
              Fly   877  876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CEP162	NP_055710.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..42
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..231
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..504		10/32 (31%)
		SMC_prok_B	<672..1385	CDD:274008	144/769 (19%)
CG42699	NP_572263.2	FlaC	<316..423	CDD:225888	23/118 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28K8R
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto91525
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR34031
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5843
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.030