Protein Alignment MRAS and RAS1

DIOPT Version :10

• Sequence 1: NP_036351.3
• Gene: MRAS / 22808
• HGNCID: 7227
• Length: 208
• Species: Homo sapiens
• Sequence 2: NP_014744.1
• Gene: RAS1 / 854268
• SGDID: S000005627
• Length: 309
• Species: Saccharomyces cerevisiae
• Alignment Length: 163
• Identity: 96/163 - (58%)
• Similarity: 129/163 - (79%)
• Gaps: 1/163 - (0%)

Human    14 YKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQWAILDVLDTAGQEEFSAMR 78
            ||:||||.||||||||||||.|..||.:|||||||||.|...||::.:|||:||||||||:||||
Yeast    11 YKIVVVGGGGVGKSALTIQFIQSYFVDEYDPTIEDSYRKQVVIDDKVSILDILDTAGQEEYSAMR 75

Human    79 EQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFPMILVANKVDLMHLRKITREQGKE 143
            |||||||:|||:|||||.:.||:.:..::|.|.||||.:..|:::|.||:||.:.|:::.|.|..
Yeast    76 EQYMRTGEGFLLVYSVTSRNSFDELLSYYQQIQRVKDSDYIPVVVVGNKLDLENERQVSYEDGLR 140

Human   144 MATKHNIPYIETSAKDPPLNVDKAFHDLVRVIR 176
            :|.:.|.|::|||||. .:|||:||:.|:|::|
Yeast   141 LAKQLNAPFLETSAKQ-AINVDEAFYSLIRLVR 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MRAS	NP_036351.3	M_R_Ras_like	12..176	CDD:133345	95/161 (59%)
		Effector region	42..50		7/7 (100%)
RAS1	NP_014744.1	small_GTPase	9..172	CDD:197466	95/161 (59%)