DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RRAS2 and rras

DIOPT Version :9

Sequence 1:	NP_036382.2	Gene:	RRAS2 / 22800	HGNCID:	17271	Length:	204	Species:	Homo sapiens
Sequence 2:	NP_001107720.1	Gene:	rras / 100135709	XenbaseID:	XB-GENE-493188	Length:	203	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	147/191 - (76%)
Similarity:	164/191 - (85%)	Gaps:	0/191 - (0%)

- Green bases have known domain annotations that are detailed below.

Human    13 EKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILDTAGQEEFGA 77
            |||:||||||||||||||||||||||||:||||||||||||.|.||.:..|||||||||||||||
Frog    12 EKYKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSIDGKQTRLDILDTAGQEEFGA 76

Human    78 MREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEG 142
            ||||||||||||||:|::.|||||.|:.||..|||||||||||||||:|||||||.|||||:||.
Frog    77 MREQYMRTGEGFLLIFAINDRGSFNEMSKFHTQILRVKDRDEFPMILVGNKADLDLQRQVTKEEA 141

Human   143 QQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVI 203
            ...||:..:.|||||||||:|||::||||||.||||||.||||:|....|:|:.|.|.|||
Frog   142 LSFARENHIPYMEASAKIRLNVDESFHELVRAIRKFQELECPPTPAVNPKKKESKSCPCVI 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RRAS2	NP_036382.2	M_R_Ras_like	13..176	CDD:133345	129/162 (80%)
RRAS2	NP_036382.2	Effector region	43..51		7/7 (100%)
rras	NP_001107720.1	M_R_Ras_like	12..175	CDD:133345	129/162 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	1	1.000	-	-		X1567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950