DRSC/TRiP Functional Genomics Resources

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Protein Alignment TFEC and tfec

DIOPT Version :10

Sequence 1:XP_011514265.1 Gene:TFEC / 22797 HGNCID:11754 Length:437 Species:Homo sapiens
Sequence 2:XP_073802243.1 Gene:tfec / 556894 ZFINID:ZDB-GENE-041210-21 Length:434 Species:Danio rerio


Alignment Length:431 Identity:213/431 - (49%)
Similarity:270/431 - (62%) Gaps:84/431 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    54 PQIYSSQLPS---FT--RVPAHLESSARPQLQKAQRQKVNSFMTLD-------HQIINPTLKWSQ 106
            |..|....||   :|  :|.:|||:| :..|.:.|.|:|..::.|.       |.:.:|.     
Zfish    41 PGPYQGSEPSAWPWTPFKVQSHLENS-KYHLNQTQAQQVKQYLALGSKLASQAHPVAHPL----- 99

Human   107 PAVPSGG-PLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEGA 170
            |....|. |::::.|....||:....:|:| ||.:....| :::.|::||:|:||:|:.||:...
Zfish   100 PGQALGTVPVMRNGHMPPVSDSSTPGSPVT-LLTLANNHD-SEFPMDEVIDDLIGLENGFKDGSL 162

Human   171 D--SP-LLMQR--TLSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQK 230
            |  .| ::||.  :|:.|:|:||..:|                         |.|||.|||||||
Zfish   163 DCMEPGIIMQNNVSLNSSMLEVYGADQ-------------------------EHDTRVLAKERQK 202

Human   231 KDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHR 295
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||:||.|
Zfish   203 KDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQHARDLESR 267

Human   296 QKKLEQANRRLLLRIQELEIQARTHGLPTL-ASLGTVDLGAHVTKQQSHPEQ------------- 346
            |||||||||||.||||||||||..||||:: ||:|||:|.:|:.|||.|..|             
Zfish   268 QKKLEQANRRLQLRIQELEIQAHAHGLPSMTASMGTVELSSHLLKQQHHQTQATAASQSAQAPQS 332

Human   347 -----------NSVDYCQQLTVSQGPS--PELCDQAIAFSDPLSYFTDLSFSAALKEE-QRLDGM 397
                       :|.:|.|:.::   ||  .|..|.:..||||||:|||. |.:.|||| ||||.:
Zfish   333 TQPPIYPQEGVSSPEYTQRTSL---PSIVGEQSDGSNNFSDPLSHFTDF-FCSTLKEEHQRLDEI 393

Human   398 LLDDTISPFGTDPLLSATSP-AVSKESSRRSSFSSDDGDEL 437
            |:||.:|||||||||||.|| |.||||||||||||::.|:|
Zfish   394 LMDDPLSPFGTDPLLSAGSPTAASKESSRRSSFSSEETDDL 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TFECXP_011514265.1 bHLHzip_TFEC 226..310 CDD:381495 79/83 (95%)
DUF3371 315..434 CDD:463372 73/147 (50%)
tfecXP_073802243.1 None

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