DRSC/TRiP Functional Genomics Resources

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Protein Alignment TFEC and Tfec

DIOPT Version :10

Sequence 1:XP_011514265.1 Gene:TFEC / 22797 HGNCID:11754 Length:437 Species:Homo sapiens
Sequence 2:XP_006505098.1 Gene:Tfec / 21426 MGIID:1333760 Length:353 Species:Mus musculus


Alignment Length:389 Identity:262/389 - (67%)
Similarity:289/389 - (74%) Gaps:37/389 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    49 LVPARPQIYSSQLPSFTRVPAHLESSARPQLQKAQRQKVNSFMTLDHQIINPTLKWSQPAVPSGG 113
            |:|     |....|..  |.||:|:|.:|||||||.|:|..|||.|.::.:.|||.:||...|..
Mouse     2 LIP-----YIRSYPPM--VQAHVETSTKPQLQKAQTQQVTPFMTFDCRVCDQTLKRAQPPAASCM 59

Human   114 PLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEGADSPLLMQR 178
            ||.:|...:.|||||...||.|.|||:||:|...:||                            
Mouse    60 PLAEHEPMSPDSDAGCAGNPFTNLLALGKKDGAEKWH---------------------------- 96

Human   179 TLSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRY 243
             ||||||||||.|||||..|.|||.|.|||.|||::||.|||.||||||||||||||||||||||
Mouse    97 -LSGSILDVYSDEQGISSANAGLTDAPCPSILPMRKEIAETDGRALAKERQKKDNHNLIERRRRY 160

Human   244 NINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLL 308
            |||||||||||||||||||||||||||||||||:|||||||||||||||||||||||.|||:|.|
Mouse   161 NINYRIKELGTLIPKSNDPDMRWNKGTILKASVDYIKWLQKEQQRARELEHRQKKLEHANRQLRL 225

Human   309 RIQELEIQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVDYCQQLTVSQGPSPELCDQAIAFS 373
            ||||||||||.||||.||||||.|:|.|:||||:|||:|....|.|||.:||.|||..:||:|||
Mouse   226 RIQELEIQARAHGLPILASLGTADVGTHITKQQTHPERNLGGCCLQLTPTQGTSPEFYEQAVAFS 290

Human   374 DPLSYFTDLSFSAALKEEQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL 437
            ||||:|||||||||||||||||||||.|||.||||||||||.||||||.|| |||.||:|||||
Mouse   291 DPLSHFTDLSFSAALKEEQRLDGMLLSDTICPFGTDPLLSAISPAVSKASS-RSSLSSEDGDEL 353

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TFECXP_011514265.1 bHLHzip_TFEC 226..310 CDD:381495 79/83 (95%)
DUF3371 315..434 CDD:463372 90/118 (76%)
TfecXP_006505098.1 bHLHzip_MITF 135..238 CDD:381496 96/102 (94%)
DUF3371 232..336 CDD:463372 79/103 (77%)

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