Protein Alignment TFEC and tfec

DIOPT Version :10

• Sequence 1: XP_011514265.1
• Gene: TFEC / 22797
• HGNCID: 11754
• Length: 437
• Species: Homo sapiens
• Sequence 2: XP_002935013.2
• Gene: tfec / 100487610
• XenbaseID: XB-GENE-986001
• Length: 375
• Species: Xenopus tropicalis
• Alignment Length: 383
• Identity: 229/383 - (59%)
• Similarity: 288/383 - (75%)
• Gaps: 23/383 - (6%)

Human    63 SFTRVPAHLESSARPQLQKAQRQKVNSFMTLDHQIINPTLKWSQPAV--PSG-GPLVQHAHTTLD 124
            |:..|.||||:..:..||::|||:|..::.|.::....||.:|.|..  |:| .|.:::.|.:.|
 Frog     8 SYYEVQAHLENPTKYHLQQSQRQQVKQYLNLGNKFSTQTLSYSHPHAIQPTGIVPTLRNGHMSPD 72

Human   125 SDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEG---ADSPLLMQRT--LSGSI 184
            :|...|:||:|||:.:|...:|   .||:||:|||.:||||.::|   .:..|||...  ||.||
 Frog    73 TDNDTTDNPITKLMPLGVNREN---EMEEVIDDIISLESSFNDDGLNCTEPTLLMSSNLPLSSSI 134

Human   185 LDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIERRRRYNINYRI 249
            ||:|:.:|.   .:|||::.:|| ||.:|||.|:||.||:|||||||||||||||||||||||||
 Frog   135 LDLYNSDQS---SDMGLSNNACP-SLGVKREATDTDNRAMAKERQKKDNHNLIERRRRYNINYRI 195

Human   250 KELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELE 314
            ||||||||||||||||||||||||||||||||||||||:.|||||||||||||||||||||||||
 Frog   196 KELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQKGRELEHRQKKLEQANRRLLLRIQELE 260

Human   315 IQARTHGLPTLASLGTVDLGAHVTKQQSHPEQNSVDYCQQLTVSQGPSPELCDQAIAFSDPLSYF 379
            ||||.|||| :.:|.||::.:.|.|||::.|..|.|:..||.||.|.:.:|||.:.:||||||:|
 Frog   261 IQARAHGLP-MPTLCTVEIASQVIKQQTYGEDMSQDFASQLPVSIGQTADLCDVSTSFSDPLSHF 324

Human   380 TDLSFSAALKEEQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL 437
            |||||||||||:     ||  :.:||:|.||.||||||.:||.||||||||:||||:|
 Frog   325 TDLSFSAALKEQ-----ML--EEMSPYGADPFLSATSPDLSKGSSRRSSFSTDDGDDL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TFEC	XP_011514265.1	bHLHzip_TFEC	226..310	CDD:381495	81/83 (98%)
		DUF3371	315..434	CDD:463372	68/118 (58%)
tfec	XP_002935013.2	MITF_TFEB_C_3_N	<11..101	CDD:464952	33/92 (36%)
		bHLHzip_TFEC	172..256	CDD:381495	81/83 (98%)
		DUF3371	261..372	CDD:463372	68/118 (58%)