Protein Alignment Slc30a1 and ZnT63C

DIOPT Version :9

• Sequence 1: NP_033605.1
• Gene: Slc30a1 / 22782
• MGIID: 1345281
• Length: 503
• Species: Mus musculus
• Sequence 2: NP_001261364.1
• Gene: ZnT63C / 38407
• FlyBaseID: FBgn0035432
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 188/504 - (37%)
• Similarity: 270/504 - (53%)
• Gaps: 110/504 - (21%)

Mouse     1 MGCWGRNRGRLLCMLLLTFMFMVLEVVVSRVTASLAMLSDSFHMLSDVLALVVALVAERFARRTH 65
            |..:...:.|||.|:.||..|..:|::|..||.|:|:::||||||.|:.|||::.::.:.:.:..
  Fly     1 MAKYSGKKCRLLSMMWLTAFFFFVEIIVGYVTNSMALVADSFHMLGDIAALVISFLSVKMSPKKW 65

Mouse    66 ATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAVERFIEPHEMQQPLVVLSVGVAGLLVNVLG 130
            :  ||||||.||||:||||||:||..|||:|.:||.:||||...:.:|.:::.||..||||||:|
  Fly    66 S--KNTFGWARAEVLGALVNAVFLVALCFSITIEACKRFIEEEPIHEPELLVIVGALGLLVNVIG 128

Mouse   131 LCLFHHHSGEGQGAGHGHSHGHG----HGHLAKGARKAGRAGVEAGAPPGRAPDQEETNTLVANT 191
            |||.:.|.|.     ||||||.|    |..|.:      .|.::.|        ::|.|....
  Fly   129 LCLLYEHGGH-----HGHSHGGGLTRNHSRLTE------LANMDEG--------EDEQNDFAY-- 172

Mouse   192 SNSNGLKADQAEPEKLRSDDPVDVQVNGNLIQESDNLEAEDNRAGQLNMRGVFLHVLGDALGSVI 256
                         ||.:...||....:|:           .:..||:||||.|||||.|||||:|
  Fly   173 -------------EKQKEKAPVKKSSHGH-----------SHDPGQMNMRGAFLHVLSDALGSII 213

Mouse   257 VVVNALVFY-FNWKGCTEDDFCTNPCFPDPCKSSVEIINSTQAPMRDAGPCWVLYLDPTLCIIMV 320
            ||::|:|.: ..||                                     :..|:||.|.|::|
  Fly   214 VVISAVVVWKTEWK-------------------------------------YRYYMDPALSIVLV 241

Mouse   321 CILLYTTYPLLKESALILLQTVPKQIDIKHLVKELRD-VDGVEEVHELHVWQLAGSRIIATAHIK 384
            .::|::.:|||:|||||||||||..|.:..:.|.|.: ||||..|||.|||||||.||||:|||:
  Fly   242 VLILHSVWPLLRESALILLQTVPTHIQVDAIQKRLLEKVDGVLAVHEFHVWQLAGDRIIASAHIR 306

Mouse   385 CEDPASYMQVAKTIKDVFHNHGIHATTIQPEFASV-------GSKSSVLP----CELACRTQ--- 435
            |.:.:.||::|:.:|:.|||.|||:|||||||:.:       |:.|..:.    |.|.|.|.
  Fly   307 CRNLSEYMKIAEKVKEFFHNEGIHSTTIQPEFSEIEGCNMSDGTSSINISGSDCCALDCPTTEEG 371

Mouse   436 CALKQCCGTRPQVHSGKDAEKAPTVSISCLELSENLEKKARRTKAEGSL 484
            |....||....:::.......:|.:   |.:  .|..::|...:| |||
  Fly   372 CVKATCCQNNNKLNQLPSPTNSPYL---CRQ--RNAARQAGDVEA-GSL 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc30a1	NP_033605.1	CzcD	6..418	CDD:224151	170/417 (41%)
		Cation_efflux	21..339	CDD:279834	116/322 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..213		15/76 (20%)
		6 X 2 AA approximate repeats of H-G	145..156		8/14 (57%)
ZnT63C	NP_001261364.1	CzcD	10..339	CDD:224151	169/412 (41%)
		Cation_efflux	21..260	CDD:279834	116/322 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3701
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H6681
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2743
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51881
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002109
OrthoInspector	1	1.000	-	-		otm43442
orthoMCL	1	0.900	-	-		OOG6_102585
Panther	1	1.100	-	-	O	PTHR45820
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2014
SonicParanoid	1	1.000	-	-		X1398
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.900