DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zik1 and CG17359

DIOPT Version :9

Sequence 1:NP_033603.2 Gene:Zik1 / 22775 MGIID:108070 Length:463 Species:Mus musculus
Sequence 2:NP_648679.1 Gene:CG17359 / 39549 FlyBaseID:FBgn0036396 Length:339 Species:Drosophila melanogaster


Alignment Length:331 Identity:93/331 - (28%)
Similarity:132/331 - (39%) Gaps:88/331 - (26%)


- Green bases have known domain annotations that are detailed below.


Mouse   169 TKKYRKSTEGRKETSHESDKSEECQSLSSQKQTLAHHPKTSNGKKLYECSKCGKTFRGKYSLDQH 233
            |:.|..|...:::....:....||...|..|:         :|...:.|.:|.:..|..|.|.: 
  Fly    22 TEPYASSNRVQEQEPVLATMLRECSGCSVHKE---------DGMPQFICVECAEAVRNAYRLRR- 76

Mouse   234 QRVHTGERPWECRDCGKFFSQ----TSHLND-HRRIHTGER-----PYECSECGKLFRQNSSLV- 287
                      :||...::|.|    ...|:| ...::.|:.     |....|.||....:..|: 
  Fly    77 ----------QCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLV 131

Mouse   288 ------------------------------------DHQKTHTGARPYECSQCGKSFSQKATLV- 315
                                                .|.|:...||.|..:.   |:|..:.|. 
  Fly   132 ELVQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDND---SWSPDSELEH 193

Mouse   316 -------------KHKRVHTGERPYKCSECGNSFSQSAILNQHRRIHTGVKPYECRECGKSFSQK 367
                         |.|||   ..||:|..|..||:|...|..|.|||||.:||:|..|.:||:||
  Fly   194 EDDDKIWNASKRGKPKRV---PGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQK 255

Mouse   368 ATLIKHQRVHTGERPYKCSECGKSFSQSSILIQHRRIHTGARPYECSQCGKSFSQKSGLIQHQVV 432
            ..|..|.|.||||||:.|..|.|.|.|...|..|.|.|||.:|::||:|.:||.|.:||.:|...
  Fly   256 GNLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSA 320

Mouse   433 HT-GER 437
            || |:|
  Fly   321 HTRGKR 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zik1NP_033603.2 KRAB 14..52 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 106..128
COG5048 <112..425 CDD:227381 86/316 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 171..211 6/39 (15%)
C2H2 Zn finger 190..209 CDD:275368 4/18 (22%)
C2H2 Zn finger 217..237 CDD:275368 5/19 (26%)
zf-H2C2_2 229..254 CDD:290200 4/24 (17%)
C2H2 Zn finger 245..265 CDD:275368 6/24 (25%)
zf-H2C2_2 257..282 CDD:290200 7/30 (23%)
C2H2 Zn finger 273..293 CDD:275368 6/56 (11%)
zf-H2C2_2 285..310 CDD:290200 7/61 (11%)
C2H2 Zn finger 301..321 CDD:275368 6/33 (18%)
zf-H2C2_2 314..338 CDD:290200 11/37 (30%)
C2H2 Zn finger 329..349 CDD:275368 8/19 (42%)
zf-H2C2_2 342..366 CDD:290200 13/23 (57%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 370..394 CDD:290200 13/23 (57%)
C2H2 Zn finger 385..405 CDD:275368 8/19 (42%)
zf-H2C2_2 398..422 CDD:290200 12/23 (52%)
C2H2 Zn finger 413..433 CDD:275368 9/19 (47%)
C2H2 Zn finger 441..461 CDD:275368
CG17359NP_648679.1 zf-AD 6..88 CDD:285071 16/85 (19%)
zf-C2H2 215..237 CDD:278523 9/21 (43%)
C2H2 Zn finger 217..237 CDD:275368 8/19 (42%)
zf-H2C2_2 229..254 CDD:290200 13/24 (54%)
C2H2 Zn finger 245..265 CDD:275368 9/19 (47%)
zf-H2C2_2 257..282 CDD:290200 13/24 (54%)
C2H2 Zn finger 273..293 CDD:275368 8/19 (42%)
zf-H2C2_2 286..310 CDD:290200 12/23 (52%)
C2H2 Zn finger 301..321 CDD:275368 9/19 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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