DRSC/TRiP Functional Genomics Resources

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Protein Alignment FHL1 and LRG1

DIOPT Version :10

Sequence 1:NP_001427698.1 Gene:FHL1 / 2273 HGNCID:3702 Length:339 Species:Homo sapiens
Sequence 2:NP_010041.2 Gene:LRG1 / 851358 SGDID:S000002399 Length:1017 Species:Saccharomyces cerevisiae


Alignment Length:174 Identity:44/174 - (25%)
Similarity:75/174 - (43%) Gaps:31/174 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    86 KCLHPLANETFVAKDNKILCNKCT--TREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNC 148
            :.|:..:..|...|:.|.:|.:|.  ...||.:.|...||:          |..:|:.||||.:|
Yeast     9 RSLNTASPMTVQVKNQKKICARCNKLVIPDSQRTKTTLKAL----------GKYYHESCFTCQDC 63

Human   149 KQVIGTGSFFPKGED---FYCVTCHETKFAKH---CVKCNKAI-----TSGGITYQDQPWHADCF 202
            ::.: ...:||...|   ...:.|....|.:|   |..|:..:     |:.|..|.::  |..|.
Yeast    64 QKPL-KPKYFPYQVDKTSESILLCQYDYFRRHNLLCHVCDTPLRGLYYTAFGYRYDEE--HFSCT 125

Human   203 VCVT-CSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPIT 245
            :|.| |..|    :.....:|.||...:..:.:|:|.||:.||:
Yeast   126 ICATPCGVK----KCFMYGNQLYCKYHFLKYFSKRCKGCEFPIS 165

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FHL1NP_001427698.1 None
LRG1NP_010041.2 LIM1_Lrg1p_like 28..90 CDD:188777 18/72 (25%)
LIM 98..149 CDD:259829 14/56 (25%)
LIM3_Lrg1p_like 419..475 CDD:188779
RhoGAP_fLRG1 728..959 CDD:239862
Blue background indicates that the domain is not in the aligned region.

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