DRSC/TRiP Functional Genomics Resources

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Protein Alignment FHL1 and esn

DIOPT Version :9

Sequence 1:XP_006724806.1 Gene:FHL1 / 2273 HGNCID:3702 Length:339 Species:Homo sapiens
Sequence 2:NP_001260760.1 Gene:esn / 53557 FlyBaseID:FBgn0263934 Length:1134 Species:Drosophila melanogaster


Alignment Length:272 Identity:68/272 - (25%)
Similarity:102/272 - (37%) Gaps:58/272 - (21%)


- Green bases have known domain annotations that are detailed below.


Human    14 VGTMAEKFDCHYCRDPLQGKK---YVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNR 75
            |..::::..|..|.:||.|..   :.|:.|...|                               
  Fly   584 VRLLSDERPCKGCEEPLSGGDIVVFAQRLGAQLC------------------------------- 617

Human    76 FWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 140
             ||..||.|:.|...|.:..:..:|..:.|.:.......|:|..| ..|:..|:..|.:|..||.
  Fly   618 -WHPGCFVCSVCKELLVDLIYFQRDGNLYCGRHHAETQKPRCSAC-DEIIFSDECTEAEGRTWHM 680

Human   141 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAI--TSGGITYQDQPWHA--DC 201
            ..|.|..|:..:|...:..:....||:.|.:|.||::|..|.:.|  ..|.:::..|.|||  .|
  Fly   681 KHFACQECEHQLGGQRYIMREGKPYCLACFDTMFAEYCDYCGEVIGVDQGQMSHDGQHWHATDQC 745

Human   202 FVCVTCSKKLAGQRFTAVEDQYYC-VDCYKNFVAKKCAGCKNPITGKRTVS----RVSHPV---S 258
            |.|.||...|.|:.|.......|| :.|.|.          .|.|...|.|    |.:|..   |
  Fly   746 FSCCTCRCSLLGRPFLPRRGTIYCSIACSKG----------EPPTPSDTSSGPQLRPTHRASTSS 800

Human   259 KARKPPVCHGKR 270
            :..|.|...|:|
  Fly   801 QIAKSPRRGGER 812

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FHL1XP_006724806.1 LIM <21..49 CDD:413332 8/30 (27%)
LIM1_FHL1 56..109 CDD:188730 9/52 (17%)
LIM2_FHL1 117..174 CDD:188808 16/56 (29%)
LIM3_FHL1 178..230 CDD:188813 19/56 (34%)
esnNP_001260760.1 PET_Prickle 492..588 CDD:193602 1/3 (33%)
LIM1_Prickle 593..651 CDD:188799 17/89 (19%)
LIM2_Prickle 656..711 CDD:188802 16/55 (29%)
LIM3_Prickle 716..774 CDD:188804 18/57 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1704
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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