Protein Alignment FHL1 and pxl1

DIOPT Version :10

• Sequence 1: NP_001427698.1
• Gene: FHL1 / 2273
• HGNCID: 3702
• Length: 339
• Species: Homo sapiens
• Sequence 2: NP_596112.1
• Gene: pxl1 / 2540856
• PomBaseID: SPBC4F6.12
• Length: 438
• Species: Schizosaccharomyces pombe
• Alignment Length: 229
• Identity: 56/229 - (24%)
• Similarity: 90/229 - (39%)
• Gaps: 40/229 - (17%)

Human     1 MASHRHSGPSSYKVGTMAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGA 65
            ::||..:.|..|:..  :|| .||.|...|:..:.                           |.|
pombe   239 VSSHTSTKPVLYRGN--SEK-SCHSCGGSLRAGRI---------------------------ISA 273

Human    66 DSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQN 130
            ..|::       |..||:|..|...|.:..|..::.|..|:.....:.||:||.|...|  .||.
pombe   274 SGKKL-------HPQCFKCDTCSQNLEHVGFYYREGKFYCHLDYHEQFSPRCKHCKTPI--EDQA 329

Human   131 VEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY-CVTCHETKFAKHCVKCNKAITSGGITYQD 194
            |......:|::...|:.|.:|..........:|.| |.||::.|:|..|.||.|.|....:...|
pombe   330 VHINNDWFHENHHFCAGCSEVFNVNIPCIYRDDLYWCQTCYDNKYAVKCKKCRKPILGISVKGSD 394

Human   195 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDC 228
            ..:|:.|:.|..|:..|..:.:..:|:...|..|
pombe   395 GEYHSQCWTCGACNALLGDEGYFMIENTPICRPC 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FHL1	NP_001427698.1	None
pxl1	NP_596112.1	LIM	258..314	CDD:395333	16/89 (18%)
		LIM	318..370	CDD:259829	15/53 (28%)
		LIM	378..428	CDD:259829	13/49 (27%)