DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zfp239 and CG4854

DIOPT Version :9

Sequence 1:	NP_001001792.1	Gene:	Zfp239 / 22685	MGIID:	1306812	Length:	201	Species:	Mus musculus
Sequence 2:	NP_650860.1	Gene:	CG4854 / 42391	FlyBaseID:	FBgn0038766	Length:	319	Species:	Drosophila melanogaster

Alignment Length:	145	Identity:	59/145 - (40%)
Similarity:	81/145 - (55%)	Gaps:	6/145 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse    34 FKCDRCGKGFSQSSKLHIHKRVHTGEKPYACEECGMSFSQRSNLHIHQRVHTGERPYKCGECGKG 98
            |.|:.|...:|:..||..|.:||:.:||:.||.|...|.|...|..|...|||.|||||..|...
  Fly   178 FTCNICNNVYSERVKLTNHMKVHSAKKPHECEICHKRFRQTPQLARHMNTHTGNRPYKCDYCDSR 242

Mouse    99 FSQSSNLHIHRCTHTGEKPYQCYECGKGFSQSSDLRIHLRVHTGEKPYHCGKCGQGFSQSSKLLI 163
            |:..|....|:..||.|:||:|..|.:.|..|:.||:||:.||||:|:.|..|.:.|||    |.
  Fly   243 FADPSTRIKHQRIHTNERPYKCEFCSRSFGYSNVLRVHLKTHTGERPFSCQYCQKSFSQ----LH 303

Mouse   164 HQRVHTGEKPYECSK 178
            |:..|  ||.::.:|
  Fly   304 HKNSH--EKSHKRTK 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zfp239	NP_001001792.1	COG5048	<4..148	CDD:227381	48/113 (42%)
		C2H2 Zn finger	8..28	CDD:275368
		C2H2 Zn finger	36..56	CDD:275368	6/19 (32%)
		C2H2 Zn finger	64..84	CDD:275368	7/19 (37%)
		C2H2 Zn finger	92..112	CDD:275368	5/19 (26%)
		SFP1	<114..201	CDD:227516	27/65 (42%)
		C2H2 Zn finger	120..140	CDD:275368	8/19 (42%)
		C2H2 Zn finger	148..168	CDD:275368	7/19 (37%)
		C2H2 Zn finger	176..196	CDD:275368	1/3 (33%)
CG4854	NP_650860.1	zf-AD	12..>57	CDD:285071
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		zf-H2C2_2	193..217	CDD:290200	10/23 (43%)
		COG5048	201..>258	CDD:227381	22/56 (39%)
		C2H2 Zn finger	208..228	CDD:275368	7/19 (37%)
		zf-H2C2_2	221..244	CDD:290200	11/22 (50%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		zf-H2C2_2	251..273	CDD:290200	9/21 (43%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		zf-H2C2_2	277..301	CDD:290200	12/23 (52%)
		C2H2 Zn finger	292..312	CDD:275368	10/25 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	140	1.000	Inparanoid score	I4481
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050