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Protein Alignment FGR and Fgr

DIOPT Version :9

Sequence 1:	NP_001036194.1	Gene:	FGR / 2268	HGNCID:	3697	Length:	529	Species:	Homo sapiens
Sequence 2:	NP_034338.3	Gene:	Fgr / 14191	MGIID:	95527	Length:	517	Species:	Mus musculus

Alignment Length:	529	Identity:	445/529 - (84%)
Similarity:	472/529 - (89%)	Gaps:	12/529 - (2%)

- Green bases have known domain annotations that are detailed below.

Human     1 MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGF 65
            |||||||||||  .:|||.||||||||..|.:.|.||||:.|.:|.|          .|..:|.|
Mouse     1 MGCVFCKKLEP--ASKEDVGLEGDFRSQTAEERYFPDPTQGRTSSVF----------PQPTSPAF 53

Human    66 LDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPS 130
            |::|.:|.:||.|||:|:|||||||||.||||||||||||||||||.|||||||||||..|.:||
Mouse    54 LNTGNMRSISGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGHRGYVPS 118

Human   131 NYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHV 195
            |||||||||||||||||||.||||||||||.||||||||||||||||||||||||||||.||||:
Mouse   119 NYVAPVDSIQAEEWYFGKISRKDAERQLLSSGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHI 183

Human   196 KHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISR 260
            |||||||||.||||||||.||:|:|:||:||||||||||.||.||||..||||||||||||||.|
Mouse   184 KHYKIRKLDTGGYYITTRAQFDSIQDLVRHYMEVNDGLCYLLTAPCTTTKPQTLGLAKDAWEIDR 248

Human   261 SSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVV 325
            :||.|||||||||||||||||||.||||||||||||||||||||||||:||||||||||||||||
Mouse   249 NSIALERRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVV 313

Human   326 SEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILV 390
            |||||||||||||:||||||||:.|||:|.||.||||||||||||||||||||||||||||||||
Mouse   314 SEEPIYIVTEFMCYGSLLDFLKDREGQNLMLPHLVDMAAQVAEGMAYMERMNYIHRDLRAANILV 378

Human   391 GERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKG 455
            ||.|.||||||||||||:|:||||.||:||||||||||||||||||:||||||||||||||||||
Mouse   379 GEYLICKIADFGLARLIEDNEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKG 443

Human   456 RIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAE 520
            |:||||||.||||||||.||||||||||||||||.|||.||||||||||||||||||||||||.|
Mouse   444 RVPYPGMNNREVLEQVEHGYHMPCPPGCPASLYEVMEQAWRLDPEERPTFEYLQSFLEDYFTSTE 508

Human   521 PQYQPGDQT 529
            |||||||||
Mouse   509 PQYQPGDQT 517

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.