DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sf1 and qkr58E-3

DIOPT Version :9

Sequence 1:	NP_001104261.1	Gene:	Sf1 / 22668	MGIID:	1095403	Length:	639	Species:	Mus musculus
Sequence 2:	NP_001246460.1	Gene:	qkr58E-3 / 37559	FlyBaseID:	FBgn0022984	Length:	317	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	83/350 - (23%)
Similarity:	134/350 - (38%)	Gaps:	89/350 - (25%)

- Green bases have known domain annotations that are detailed below.

Mouse    76 PEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERH----------TLITEMV------ALNPDFK 124
            |.:.:....|.::.: .|||....:....|:|||.          .||.|.|      ...|..:
  Fly     4 PSEFTEKQPPTHDHQ-PRLNEVAQKFLADLDEERQRLSADFPLCALLIDEAVDRVYCTGRIPGKE 67

Mouse   125 PPAD-YKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKV 188
            ..|| ||....:::.||.:|..:||:.||.|.::||:||:|:.:::|...||.|:|:.|:::
  Fly    68 FYADVYKQKPMKITQKVFVPVKQYPKFNFTGKILGPKGNSLRRLQEETQCKIAIKGRSSIRD--- 129

Mouse   189 GRKDGQMLPGEDEPLHA-------------LVTANTMENVKKAVEQIRNILKQGIETPEDQNDLR 240
             |...:.|....:|.:|             ...|.....:..|:.:||..|     .|:..:::.
  Fly   130 -RNKEEQLRSTGDPRYAHLQKDLFLEVSTVATPAECYARIAYALAEIRKYL-----IPDKNDEVS 188

Mouse   241 KMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQD 305
            ..|||||..::   .|....|..| .....||:.:    .|.||..:          |.|
  Fly   189 HEQLRELMEMD---PESAKNIHGP-NLEAYRSVFD----KKFGGNSN----------GAP----- 230

Mouse   306 KARMDKEYLSLMAELGEAP--------VPASVGSTSGPATTPLA---SAPRPA-----APASNPP 354
                  :|::|:....|.|        |.........|...|..   |.|||:     |.|...|
  Fly   231 ------KYINLIKRAAENPPEVDDVEEVAYEYEHRMPPKRPPTGYEYSKPRPSIIPTNAAAYKRP 289

Mouse   355 PPSLMSTTQSRPPWMNSGPSENRPY 379
            .|:.|...: .||..:..|:   ||
  Fly   290 YPTDMKRMR-EPPIKSYKPN---PY 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sf1	NP_001104261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		Nuclear localization signal. /evidence=ECO:0000255	15..19
		MSL5	17..257	CDD:227503	52/210 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..94		2/17 (12%)
		ZnF_C2HC	278..293	CDD:197667	3/14 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..584		16/62 (26%)
qkr58E-3	NP_001246460.1	SF1_like-KH	81..200	CDD:239088	34/130 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.731683	Normalized mean entropy	S1317
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760