DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FGG and CG7668

DIOPT Version :10

Sequence 1:NP_068656.2 Gene:FGG / 2266 HGNCID:3694 Length:453 Species:Homo sapiens
Sequence 2:NP_649170.1 Gene:CG7668 / 40190 FlyBaseID:FBgn0036929 Length:422 Species:Drosophila melanogaster


Alignment Length:400 Identity:101/400 - (25%)
Similarity:163/400 - (40%) Gaps:79/400 - (19%)


- Green bases have known domain annotations that are detailed below.


Human    35 CILDERFGSYCPTTCGIADFLSTYQTKVDKDLQSLEDILHQVENKTSEVKQLIKAIQLTYNPDES 99
            ||.|:            .||:.|.|..:|...|:.|..:.:::.:..:::..:...::|...::.
  Fly    80 CIKDK------------DDFIKTLQLSIDLVTQTKEMTIQKLQTQIMDLQSDLDLSRITIKKNDG 132

Human   100 SKPNMIDAATLKSRKMLE-EIMKYEASILTHDSSIRYLQEIYNSNNQKIVNL-------KEKVAQ 156
            ..........:|.||.|. |..|:...    :..|..:::|.||...:|..|       |.|:.|
  Fly   133 GNCAPAHDKVVKERKELNMENGKFREG----NDQIVEIEKILNSKEAEIARLEFKIDESKLKIVQ 193

Human   157 LEAQCQEPCKDTVQI------HDITGKDCQDIANKGAKQSGLYFIKPLKANQQFL-VYCEIDGSG 214
            ||...:...:..|::      :::..||..:....|:.:.....:..|...:.|. |:.:|..:|
  Fly   194 LEGAVKAKDEKIVKMTEILSEYNVNNKDHDEFVLLGSSKLPSIKLVTLPDFEPFASVFEDIPSAG 258

Human   215 NGWTVFQKRLDGSVD--FKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELE 277
            .||.:.|:|:|||.|  .:.|.|   .|.|.|.    .|||||.:|:|.::|...:  .|.::|.
  Fly   259 RGWMIIQRRIDGSFDNATESNII---TGCGDLG----GEFWLGLQKLHKMTTHRRM--ELYIQLV 314

Human   278 DWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWD 342
            |::..::.|.|..|.:|.|..||:|.......|:||||              |.||         
  Fly   315 DFDNASAYARYDNFVIGDEKQKYKLLSLGEYSGNAGDA--------------FRSH--------- 356

Human   343 NDNDKFEGNCAEQDGSGWW--MNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKT-RWYS 404
             .|....||....:.|.||  || |   :|||.|..    ||.....  .:||.|..|.. ..|.
  Fly   357 -INHIIVGNPFAMESSKWWGTMN-C---NLNGKYRN----SKVELDT--TDGIWWGNWNVGNRYP 410

Human   405 MKKTTMKIIP 414
            :|...|.|.|
  Fly   411 LKSCKMLIRP 420

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FGGNP_068656.2 Fib_alpha 30..172 CDD:462570 29/150 (19%)
Fibrinogen_C 175..414 CDD:395095 71/244 (29%)
Gamma-chain polymerization, binding amino end of another fibrin alpha chain 400..422 4/15 (27%)
Platelet aggregation and Staphylococcus clumping 423..437
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 424..453
CG7668NP_649170.1 GumC <52..>242 CDD:442439 32/177 (18%)
FReD 245..421 CDD:412152 67/218 (31%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.