Protein Alignment FGG and CG30280

DIOPT Version :10

• Sequence 1: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Sequence 2: NP_611641.6
• Gene: CG30280 / 37522
• FlyBaseID: FBgn0050280
• Length: 288
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 94/284 - (33%)
• Similarity: 132/284 - (46%)
• Gaps: 33/284 - (11%)

Human   136 LQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKA 200
            |:.||......:..|:|.:.|||..........|    |....|   ...|..::||:.:| :..
  Fly    31 LEAIYEQAENALSTLQESLLQLETNGTLNTSPDV----IYPTSC---LTSGDLENGLHTLK-VPG 87

Human   201 NQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQ 265
            ...|.||||...:|.||.|.|||..|::.|.:||.:||.|||:|    ..|::||.|||..::..
  Fly    88 LSPFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNL----MDEYFLGLEKIRALTAL 148

Human   266 SAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFF 330
            .  |:.|.|.|||::.....|.:..|.:|.|.|.|.:.......|.|||:              .
  Fly   149 E--PHELYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDS--------------L 197

Human   331 TSHNGMQFSTWDNDND-KFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGII 394
            .||..|:|||:|.||| :|..|||.....|||.|.|...:|||.|..||.|.::.    :..|:.
  Fly   198 RSHRKMKFSTYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEESL----FARGMC 258

Human   395 WATWKTRWYSMKKTTMKIIPFNRL 418
            |.:|:...|..:.|.|.|.|..|:
  Fly   259 WRSWRGHNYGYRVTQMMIRPKCRM 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGG	NP_068656.2	Fib_alpha	30..172	CDD:462570	9/35 (26%)
		Fibrinogen_C	175..414	CDD:395095	82/239 (34%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422		6/19 (32%)
		Platelet aggregation and Staphylococcus clumping	423..437
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453
CG30280	NP_611641.6	FReD	65..279	CDD:238040	83/241 (34%)