Protein Alignment FGG and CG5550

DIOPT Version :10

• Sequence 1: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Sequence 2: NP_001246376.1
• Gene: CG5550 / 36883
• FlyBaseID: FBgn0034160
• Length: 250
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 74/251 - (29%)
• Similarity: 115/251 - (45%)
• Gaps: 35/251 - (13%)

Human   169 VQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFL-VYCEIDGSGNGWTVFQKRLDGSVDFKK 232
            :|.:......|:::   ..|:||   ::.::.....: |||::..:|.||.|.|:|:....:|.:
  Fly    29 IQTYKKYSSSCKEL---NPKKSG---VQKIQVGSDVIEVYCDVTIAGKGWLVVQRRVSVEENFYR 87

Human   233 NWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEA 297
            ||..|:.|||.|.    ..|::|...::.||  |..|..|.:||.|:.|....|.|::|.||...
  Fly    88 NWTSYQTGFGDLK----GNFFIGLNNLNKIS--SLQPQELYIELVDFAGEKRYAHYSVFHVGNVY 146

Human   298 DKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWM 362
            ..|.:|......|.|||:              .:.|....|||:|.|||....|||.:....||.
  Fly   147 SNYPITQLGAYSGTAGDS--------------LSYHLYQPFSTFDRDNDNATINCAARYMGAWWY 197

Human   363 NKC----HAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIP 414
            .:|    ...:|||.|. ||.:   :.|..:.:||:|..||...||.|...:.:.|
  Fly   198 RECLSRIPCSNLNGAYL-GGNH---TDPALFGSGIVWGEWKGFTYSYKTVNIMVRP 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGG	NP_068656.2	Fib_alpha	30..172	CDD:462570	1/2 (50%)
		Fibrinogen_C	175..414	CDD:395095	72/243 (30%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422		4/15 (27%)
		Platelet aggregation and Staphylococcus clumping	423..437
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453
CG5550	NP_001246376.1	FReD	34..250	CDD:238040	73/246 (30%)