Protein Alignment FGG and CG1791

DIOPT Version :10

• Sequence 1: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Sequence 2: NP_572591.1
• Gene: CG1791 / 31927
• FlyBaseID: FBgn0030163
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 278
• Identity: 77/278 - (27%)
• Similarity: 119/278 - (42%)
• Gaps: 56/278 - (20%)

Human   146 KIVNLKEKVAQLEAQCQE----------------PCKDTVQIH--------DITGKDCQDIANKG 186
            ::.|||.::.:|:...:|                |...:||..        |.|.::|.|
  Fly    67 ELQNLKTELNELQGLIEEYKNQGTGIPIATRLLRPLPASVQTFPLALATPPDDTPRNCYD----- 126

Human   187 AKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTE 251
             ::.|...|:.....:.|...|:......||.|...|.|||.||.|:|..||.|||.|:    :|
  Fly   127 -EKHGQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFGALN----SE 186

Human   252 FWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAF 316
            |::|.:|:|.::...  .:.|.:.::..:|....|.|..|.:|.|::||.|   |..|...|||.
  Fly   187 FFIGLDKLHRLTNSE--HHELLIIMKKKSGEERFALYDHFSIGSESEKYLL---YVLGAYKGDAG 246

Human   317 DGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNK-CHAGHLNGVYYQGGTY 380
            |...:           |.|.:|:|:|.|||....|||......||..: |...:|.|.:     .
  Fly   247 DSLRY-----------HAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFGTF-----Q 295

Human   381 SKASTPNGYDNGIIWATW 398
            ||.....||..||:|.::
  Fly   296 SKYGQEIGYFKGILWKSF 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGG	NP_068656.2	Fib_alpha	30..172	CDD:462570	8/41 (20%)
		Fibrinogen_C	175..414	CDD:395095	68/225 (30%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422
		Platelet aggregation and Staphylococcus clumping	423..437
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453
CG1791	NP_572591.1	FReD	119..331	CDD:238040	68/226 (30%)