Protein Alignment FGG and CG30281

DIOPT Version :10

• Sequence 1: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Sequence 2: NP_726164.1
• Gene: CG30281 / 246525
• FlyBaseID: FBgn0050281
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 96/295 - (32%)
• Similarity: 142/295 - (48%)
• Gaps: 33/295 - (11%)

Human   136 LQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKA 200
            |..:|......:.:||.::.:|:...:|..::......|....|   ...|...:|::.|: :..
  Fly    25 LDLVYKKAESMVSSLKIRLEELKQSYKEITEERGSHETINPSSC---LAAGINSNGIHVIE-VPG 85

Human   201 NQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQ 265
            .:.|.|||:...:|:||||.|:|.|||.:|.:.|.:|.:|||.||    .||::|.||:|.::|
  Fly    86 LEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGELS----GEFFMGLEKLHFLTT- 145

Human   266 SAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFF 330
             |.||.|.|.:||:||....|.|..|.:|..:..|.|:......|||||:              .
  Fly   146 -AEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDS--------------L 195

Human   331 TSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIW 395
            ..|.||.|||:|:| |...| ||......||.::|...:|||.|.:||.:.    |.....||.|
  Fly   196 RYHKGMPFSTFDHD-DTGHG-CARIYVGAWWYDQCQRSNLNGQYLEGGRFE----PKMSGRGITW 254

Human   396 ATWKTRWYSMKKTTMKIIP--FNRLTIGEGQQHHL 428
            .:|:...|..|...|.|.|  .|.|. .:|.|:.|
  Fly   255 MSWRGYDYGYKFVQMMIRPKCSNNLR-RQGMQNAL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGG	NP_068656.2	Fib_alpha	30..172	CDD:462570	6/35 (17%)
		Fibrinogen_C	175..414	CDD:395095	83/238 (35%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422		7/23 (30%)
		Platelet aggregation and Staphylococcus clumping	423..437		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453		2/5 (40%)
CG30281	NP_726164.1	FReD	63..274	CDD:238040	84/240 (35%)