DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ywhaq and 14-3-3epsilon

DIOPT Version :9

Sequence 1:	NP_035869.1	Gene:	Ywhaq / 22630	MGIID:	891963	Length:	245	Species:	Mus musculus
Sequence 2:	NP_732309.1	Gene:	14-3-3epsilon / 42186	FlyBaseID:	FBgn0020238	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	159/243 - (65%)
Similarity:	190/243 - (78%)	Gaps:	2/243 - (0%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 EKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIE 66
            |:...:.||||||||||||:|...||.|.....||:.|||||||||||||:|.||::||:|:|||
  Fly     3 ERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITSIE 67

Mouse    67 QKTDT--SDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYL 129
            ||.:.  :::||::||.||.:||.|||.||:.:|.:|:|:||..||:.||||||.||||||.|||
  Fly    68 QKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIPCATSGESKVFYYKMKGDYHRYL 132

Mouse   130 AEVACGDDRKQTIENSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKT 194
            ||.|.|.|||...|||..||:.|.||:..::.||||||||||||||||||||||:|:.||.|||.
  Fly   133 AEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKA 197

Mouse   195 AFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEG 242
            |||:||||||||:|:||||||||||||||||||||||...||.|...|
  Fly   198 AFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAG 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ywhaq	NP_035869.1	14-3-3_theta	1..234	CDD:206759	155/233 (67%)
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	151/228 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830