DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ywhag and 14-3-3epsilon

DIOPT Version :9

Sequence 1:	NP_061359.2	Gene:	Ywhag / 22628	MGIID:	108109	Length:	247	Species:	Mus musculus
Sequence 2:	NP_732309.1	Gene:	14-3-3epsilon / 42186	FlyBaseID:	FBgn0020238	Length:	262	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	158/249 - (63%)
Similarity:	194/249 - (77%)	Gaps:	6/249 - (2%)

- Green bases have known domain annotations that are detailed below.

Mouse     1 MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISS 65
            |.:||..|.||:|||||||||:|..|||.|..::..|:.|||||||||||||:||||:|||:|:|
  Fly     1 MTERENNVYKAKLAEQAERYDEMVEAMKKVASMDVELTVEERNLLSVAYKNVIGARRASWRIITS 65

Mouse    66 IEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDY 130
            ||||....|.|:|:||::.||.::||||..:|.|:|::|:.:||. |: |..||||||.||||||
  Fly    66 IEQKEENKGAEEKLEMIKTYRGQVEKELRDICSDILNVLEKHLIP-CA-TSGESKVFYYKMKGDY 128

Mouse   131 YRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACH 195
            :|||||.|||..|....|:|..||..|.:|:...:.||||||||||||:|||||||.|:|::||.
  Fly   129 HRYLAEFATGSDRKDAAENSLIAYKAASDIAMNDLPPTHPIRLGLALNFSVFYYEILNSPDRACR 193

Mouse   196 LAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQ----DDDGGEG 245
            |||.||||||||||||:|:||||||||||||||||||||||.|    |.:.|:|
  Fly   194 LAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQAEEVDPNAGDG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ywhag	NP_061359.2	14-3-3_gamma	2..247	CDD:206760	157/248 (63%)
14-3-3epsilon	NP_732309.1	14-3-3_epsilon	4..233	CDD:206757	150/230 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830