DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ywhag and 14-3-3zeta

DIOPT Version :9

Sequence 1:	NP_061359.2	Gene:	Ywhag / 22628	MGIID:	108109	Length:	247	Species:	Mus musculus
Sequence 2:	NP_001014515.1	Gene:	14-3-3zeta / 36059	FlyBaseID:	FBgn0004907	Length:	248	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	182/248 - (73%)
Similarity:	206/248 - (83%)	Gaps:	9/248 - (3%)

- Green bases have known domain annotations that are detailed below.

Mouse     2 VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSI 66
            ||:|:|||||:||||:|||||||.|||:|||....||||||||||||||||||||||||||||||
  Fly     4 VDKEELVQKAKLAEQSERYDDMAQAMKSVTETGVELSNEERNLLSVAYKNVVGARRSSWRVISSI 68

Mouse    67 EQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYY 131
            ||||.|  :.:|.::.|.|||::||||..:|.:||.|||.|||...|..  ||||||||||||||
  Fly    69 EQKTEA--SARKQQLAREYRERVEKELREICYEVLGLLDKYLIPKASNP--ESKVFYLKMKGDYY 129

Mouse   132 RYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHL 196
            |||||||||:.|.|||:.|:.||.:|.:|||..||||||||||||||:|||||||.|:|::||.|
  Fly   130 RYLAEVATGDARNTVVDDSQTAYQDAFDISKGKMQPTHPIRLGLALNFSVFYYEILNSPDKACQL 194

Mouse   197 AKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDD-----DGGE 244
            ||.|||||||||||||||||||||||||||||||||||||.|.|     :||:
  Fly   195 AKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDTQGDEAEPQEGGD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ywhag	NP_061359.2	14-3-3_gamma	2..247	CDD:206760	182/248 (73%)
14-3-3zeta	NP_001014515.1	14-3-3	5..234	CDD:413191	175/232 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850043
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5040
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53683
OrthoDB	1	1.010	-	-		D1176818at2759
OrthoFinder	1	1.000	-	-		FOG0000128
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18860
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.820