Protein Alignment FGFR3 and SHO1

DIOPT Version :10

• Sequence 1: XP_006713931.1
• Gene: FGFR3 / 2261
• HGNCID: 3690
• Length: 811
• Species: Homo sapiens
• Sequence 2: NP_011043.1
• Gene: SHO1 / 856854
• SGDID: S000000920
• Length: 367
• Species: Saccharomyces cerevisiae
• Alignment Length: 84
• Identity: 16/84 - (19%)
• Similarity: 27/84 - (32%)
• Gaps: 34/84 - (40%)

Human   280 DAQPHIQWLKHVEVNGSKVGP--------------DGTPYVTVLKSWISESVEADVRLRLANVSE 330
            :|.|..:|:....:.|.:..|              :.|||                :..:.|.:.
Yeast   147 NASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPY----------------QNNVYNDAI 195

Human   331 RDGGEYLCRATNFIGVAEK 349
            ||.|    .||.|.|..::
Yeast   196 RDSG----YATQFDGYPQQ 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGFR3	XP_006713931.1	Ig	37..109	CDD:472250
		Ig strand B	57..61	CDD:409362
		Ig strand C	69..75	CDD:409362
		Ig strand E	92..96	CDD:409362
		IgI_2_FGFR	151..245	CDD:409443
		Ig strand A	151..154	CDD:409443
		Ig strand A'	162..167	CDD:409443
		Ig strand B	171..179	CDD:409443
		Ig strand C	185..190	CDD:409443
		Ig strand C'	193..195	CDD:409443
		Ig strand D	204..207	CDD:409443
		Ig strand E	211..216	CDD:409443
		Ig strand F	225..232	CDD:409443
		Ig strand G	235..245	CDD:409443
		IgI_3_FGFR	253..354	CDD:409363	16/84 (19%)
		Ig strand A	253..256	CDD:409363
		Ig strand A'	260..264	CDD:409363
		Ig strand B	272..279	CDD:409363
		Ig strand C	283..290	CDD:409363	2/6 (33%)
		Ig strand D	305..310	CDD:409363	1/4 (25%)
		Ig strand E	321..326	CDD:409363	0/4 (0%)
		Ig strand F	334..342	CDD:409363	2/7 (29%)
		Ig strand G	345..353	CDD:409363	1/5 (20%)
		Protein Kinases, catalytic domain	463..797	CDD:473864
SHO1	NP_011043.1	SH3_Sho1p	304..358	CDD:212789