Protein Alignment ALDOA and Ald2

DIOPT Version :10

• Sequence 1: NP_001230106.1
• Gene: ALDOA / 226
• HGNCID: 414
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_651476.1
• Gene: Ald2 / 43189
• FlyBaseID: FBgn0039425
• Length: 364
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 206/358 - (57%)
• Similarity: 257/358 - (71%)
• Gaps: 2/358 - (0%)

Human    54 TMPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLL 118
            |..:.||  ..|.::||..|:..:|||||||||||||:..:.||.|.||.||||||||.|||:|.
  Fly     2 TTHFYYP--NKELQEELICISKALVAPGKGILAADESSAVMGKRFQLIGVENTEENRRLYRQMLF 64

Human   119 TADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLD 183
            |.|.::...|.|||.:||||:|:.|||.||.:.::.||.:.||||||...||.|:..|.||||||
  Fly    65 TTDPKIAENISGVIFYHETLHQRTDDGLPFVEALRKKGILTGIKVDKHFSPLFGSEDEFTTQGLD 129

Human   184 GLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPD 248
            .|:.|||||||:|..||||||:|||.::|||..||:|||||:||||:|||...:|||:.||:|..
  Fly   130 DLANRCAQYKKEGCSFAKWRCILKITKNTPSPQAILENANVMARYAAICQSQRLVPIISPEVLAT 194

Human   249 GDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRR 313
            |||||.|||.|.|.:||.|||||||||::||||||:|:||.||....:.....:|.:|||.|:||
  Fly   195 GDHDLDRCQKVNEILLAGVYKALSDHHVFLEGTLLQPSMVMPGLQSNKNHPPADIGVATVLAIRR 259

Human   314 TVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAA 378
            :|||||.|:.|..|.||||||:::|||||..||.||||:||::.||||.|.|:.||||||.:..|
  Fly   260 SVPPAVMGVLFCGGAQSEEEATVHLNAINNVPLCKPWAMTFAFDRALQTSILRTWGGKKEQISHA 324

Human   379 QEEYVKRALANSLACQGKYTPSGQAGAAASESL 411
            |.|.:||..||.||..|||.......:||:|.|
  Fly   325 QNELIKRCRANGLASIGKYVIGSVESSAATERL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDOA	NP_001230106.1	Glycolytic	69..418	CDD:459742	202/343 (59%)
Ald2	NP_651476.1	Glycolytic	15..357	CDD:459742	201/341 (59%)