Protein Alignment Slc6a18 and CG8850

DIOPT Version :9

• Sequence 1: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Sequence 2: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 192/645 - (29%)
• Similarity: 307/645 - (47%)
• Gaps: 131/645 - (20%)

Mouse     4 ASGMDPLVDIEDE------RPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIA 62
            |.|.:..::.|.|      |.:|...:::|.|||..:|||||:||||::...:|||||||||.|.
  Fly    38 AEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIV 102

Mouse    63 LVFEGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLN 127
            |:..|.|::|:|:.|||...||.|..: .::|.:.|:..|....:.|.:.||..::...:.:.:.
  Fly   103 LLLIGRPVYYLEVIIGQFSSRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVA 166

Mouse   128 SFQHPLPWSTCPLDLNRTGFVQECQSSGTV-------------SYFWYRQTL---NITSDISNTG 176
            ||...|||:.|.::..::     |.::|..             :..::.||:   ..:.|.:..|
  Fly   167 SFSEVLPWTYCLVEWGKS-----CVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLG 226

Mouse   177 TIQWKLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFT 241
            |..|.|.|||:|.|..:...:.:||.|:||..||.|||||:::.:.|||.:|||||.:|::|...
  Fly   227 TPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLK 291

Mouse   242 PNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAI 306
            |....|.||.||..|.||:||||::.||..:.:||:|....|..||.:||..::|:||:.|...|
  Fly   292 PQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCII 356

Mouse   307 FSVMGFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLE 371
            |.::|..|                  |:                    |.|..::|:
  Fly   357 FGILGNLA------------------FE--------------------TNTKDISQV-------- 375

Mouse   372 DFLDKSASGPGLAFIVFTEAVL---HMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLD-MG 432
                 ...|.|||||.:.||:.   ::|  .:::||||.||..||:.|..|....|:..:.| ..
  Fly   376 -----VKGGAGLAFISYPEAIAKFKYLP--QLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFT 433

Mouse   433 ILPKGIPKEVMTGVICFACFLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGMK 497
            .||..: ..|...:|.|.|   .:.:....|.:.|.:.|.:..:...::.|..|::.|..|||:|
  Fly   434 HLPHWL-LAVSASIIGFLC---GLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVK 494

Mouse   498 RFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFL----SYIVLL---IQTPPSYKAWNPQYEHF 555
            |.|.|||:|...:...||::.|.:|:|.|:|.:.:    ||..|.   :|.||.|
  Fly   495 RICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVY---------- 549

Mouse   556 PSREEKFYPGWVQVTCVLLSFLPSLWVPGVALAQ-----LLSQYKQRWKATHLESGLKLQ 610
                  :..||:            :|  |:.:.|     |::.|:|..|....:.||.:|
  Fly   550 ------YMAGWI------------IW--GLGVLQLPFWALVTIYQQPGKTFGSKFGLAMQ 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	182/612 (30%)
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	168/536 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810