Protein Alignment Slc6a18 and CG15279

DIOPT Version :9

• Sequence 1: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Sequence 2: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 198/657 - (30%)
• Similarity: 314/657 - (47%)
• Gaps: 131/657 - (19%)

Mouse    13 IEDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAI 77
            :.:||..|...:::|:|||..:|||||:||||:....:|||||||||.|.|...|.|::|:|:.|
  Fly    46 VPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIVLFLIGKPIYYLEMVI 110

Mouse    78 GQRLRRGSIGVWKTISPYLGGVGLG-CFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTCPL- 140
            ||...|||:.|: .:.|.:.|||.| .|.| |::|.||..::..:..:|:.||::|||||||..
  Fly   111 GQFSSRGSVKVF-DLCPAMKGVGAGQAFQV-FMLSTYYAALVAIIGRYFIESFRNPLPWSTCRAE 173

Mouse   141 ---------------------DLNRTGFVQECQSSGTV-SYFWY--RQTLNITSDI-SNTGTIQW 180
                                 |.....:..:.|:...: |..||  ::.|:...:| ...|...|
  Fly   174 WGIHCINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGIGLPNW 238

Mouse   181 KLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMK 245
            :|.:.|...||.|:..:.||::|:||..||.|||||:::.:.|:|.:||||:.:|:.|...|...
  Fly   239 ELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWG 303

Mouse   246 TLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVM 310
            .:.:|:||..|.||.|:|||:.||..|.::|:|...:|..:||.|:..:::||||.|...||.::
  Fly   304 KILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGIL 368

Mouse   311 GFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFLD 375
            |..|.                       .|..|:..||:
  Fly   369 GHLAH-----------------------EIGTDDIGSVV-------------------------- 384

Mouse   376 KSASGPGLAFIVFTEAVL---HMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKG 437
              ..|.|||||.:.:|:.   ::|  .::|||||.|||.||:.|........:|.:.|.
  Fly   385 --KGGAGLAFISYPDAIAKFKNLP--QIFSVLFFLMLFVLGIGSNIAMTSCSVTAIRDR------ 439

Mouse   438 IPK------EVMTGVICFACFLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGM 496
            .|.      .::..|:.|  |:..:..| ..|.|.|.:.|.|.||:..::....|:..:..|||.
  Fly   440 FPNFGQWQCSLLIAVVSF--FIGLMYIT-PGGQYMLTLVDFFGASMIALVLGIAELYTIGWIYGT 501

Mouse   497 KRFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFLSYIVLLIQTPPSYKAWNP-QYEHFPSREE 560
            .|.|.|||:|.||:.||||::.|.:::|:::..|.:.:          |..:.| .|.:......
  Fly   502 DRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVILIYF----------YATYQPLTYNNIVYPNW 556

Mouse   561 KFYPGWVQVTCVLLSFLPSLWV-------PGVAL-AQLLSQY--KQRW--------KATHLESGL 607
            .:..||: :|...:..|| :|:       ||..| |::...:  |:.|        :..|.|...
  Fly   557 SYSIGWL-ITAFGILQLP-IWMIVAIVRDPGQTLGAKIRGAFTPKKNWGPSDPLLREQYHKEIEN 619

Mouse   608 KLQESRG 614
            :|...||
  Fly   620 ELTPKRG 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	191/619 (31%)
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	190/623 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810