Protein Alignment Slc6a18 and ine

DIOPT Version :10

• Sequence 1: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Sequence 2: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 201/615 - (32%)
• Similarity: 311/615 - (50%)
• Gaps: 107/615 - (17%)

Mouse     8 DPLVDIEDE----RPK---WDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVF 65
            |..:|:.||    :|:   |.||:|::|:|||::|||||:|||||:|...|||.||:||.|.|..
  Fly   321 DSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFI 385

Mouse    66 EGIPLFYIELAIGQRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQ 130
            ..|||.::||::||...||.||....:.|...|.||....||||:|.||:.::.:.:::|..||:
  Fly   386 CSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFK 450

Mouse   131 HPLPWSTCPLDLNRTGFVQEC-------------QSSGTVS-YFWYRQTLNITSDISNTGTIQWK 181
            ..:||    :|.|......:|             .:|.|.| .|:..:.|.|:..:...|.::|:
  Fly   451 TEMPW----IDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISGGLEYPGMMRWE 511

Mouse   182 LFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLIYLFTPNMKT 246
            ||.||:..|..||....:.|:|:.||.||||.||::::.|.::|.:||.||.|||.:.|.|....
  Fly   512 LFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEGLRFFFRPKWSE 576

Mouse   247 LQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYASIAIFSVMG 311
            |:|..||::||:|.|.||.:.||..|:|||||...||..:|.|.::.||.:|||...|..||.:|
  Fly   577 LKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSLLVGIFAFSTLG 641

Mouse   312 FKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKTCHLEDFLDK 376
            ..|       |::|                                             .:..|.
  Fly   642 NLA-------LEQN---------------------------------------------TNVRDV 654

Mouse   377 SASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMGILPKGIPKE 441
            ...|||:.|:|:.:|:..||.|.:|:|:||.||..|||:|.|..:|.|:|.:.|      |.|:.
  Fly   655 IGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQFAIVEVVVTSIQD------GFPRW 713

Mouse   442 VMTG------VICFACFLSAICF----TLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGM 496
            :...      |:.|.|.:|.: |    .:|.|.|:.::.|.:|||:.::..||.:::.:...||.
  Fly   714 IKRHLGYHEIVVLFVCVISCL-FGMPNIIQGGIYYFQLMDHYAASVTIMFLAFCQMIAIAWFYGT 777

Mouse   497 KRFCDDIEWMTGRRPGLYWQVTWRVVSPMLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSREEK 561
            .|...:::.|||:.|..|.:..|.|:.|.|||.|::  :.|:....|:|.  |.:|.
  Fly   778 GRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWV--LSLINYHEPTYH--NGRYT-------- 830

Mouse   562 FYPGWVQVTCVLLSFLPSLWVPGVALAQLL 591
             ||.|......:.:....:.:||.|:...|
  Fly   831 -YPDWAYGIGWMFASFSLICIPGYAVINFL 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	197/605 (33%)
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	196/599 (33%)