Protein Alignment FGF12 and fgf12a

DIOPT Version :10

• Sequence 1: NP_066360.1
• Gene: FGF12 / 2257
• HGNCID: 3668
• Length: 243
• Species: Homo sapiens
• Sequence 2: XP_005163295.1
• Gene: fgf12a / 777735
• ZFINID: ZDB-GENE-050221-6
• Length: 257
• Species: Danio rerio
• Alignment Length: 257
• Identity: 219/257 - (85%)
• Similarity: 230/257 - (89%)
• Gaps: 17/257 - (6%)

Human     3 AAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRP- 66
            ||||||||||||||||||||||||||||.|||||.|||||||.||||||||||||:||||||||
Zfish     2 AAIASSLIRQKRQARESNSDRVSASKRRPSPSKDPRSLCERHFLGVFSKVRFCSGKKRPVRRRPD 66

Human    67 ---------------EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVV 116
                           ||||||||||||||||::|||.|||:|||.||||||||||||||||||||
Zfish    67 APSKPPQVSRKGVRLEPQLKGIVTRLFSQQGFYLQMQPDGSIDGIKDENSDYTLFNLIPVGLRVV 131

Human   117 AIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEG 181
            |||||||..|:.|||||:||||::||||||||||||||||||||||:||||||||||||||.|||
Zfish   132 AIQGVKAGFYIGMNGEGFLYSSEMFTPECKFKESVFENYYVIYSSTMYRQQESGRAWFLGLTKEG 196

Human   182 QIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST 243
            |:|||||||||||||||||:|||||||||||||||.||| ||||||||||||||||||||||
Zfish   197 QVMKGNRVKKTKPSSHFVPRPIEVCMYREPSLHEIEEKQ-RSRKSSGTPTMNGGKVVNQDST 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGF12	NP_066360.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		33/35 (94%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	11..38		25/26 (96%)
		beta-trefoil_FGF12	68..206	CDD:467014	121/137 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..243		24/26 (92%)
fgf12a	XP_005163295.1	beta-trefoil_FGF12	83..221	CDD:467014	121/137 (88%)