Protein Alignment FGF12 and bnl

DIOPT Version :10

• Sequence 1: NP_066360.1
• Gene: FGF12 / 2257
• HGNCID: 3668
• Length: 243
• Species: Homo sapiens
• Sequence 2: NP_732452.1
• Gene: bnl / 42356
• FlyBaseID: FBgn0014135
• Length: 770
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 71/276 - (25%)
• Similarity: 104/276 - (37%)
• Gaps: 75/276 - (27%)

Human    11 RQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPV------RRRPEPQ 69
            :|:..:...|:...|.|||.|:|         |..|.:.|     |....|:      .|...||
  Fly   191 QQQPMSPADNNFIGSKSKRLSNP---------RSSLNINS-----SSSNTPISNLDRNERSTVPQ 241

Human    70 LKGIVTRLFSQ---QGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNG 131
            .....|....|   :...||:..||.::||:||||::|:.....|.:..:.:|.|...||:.|:.
  Fly   242 SHLAWTSRKIQLYIKNRILQILRDGVVNGTQDENSEFTILQRSTVDVGRIKLQSVATCLYLCMDA 306

Human   132 EGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMK----------- 185
            .|..|.|..||.:|.|.|::....|..||||.:.|  :.|.::|.||..||..:
  Fly   307 CGVPYGSKDFTDDCVFNENMGLQNYNTYSSTYHSQ--ARRVFYLALNGSGQPRRTQIPASRSLGK 369

Human   186 ----GNRVKKTKPS----------------SHFV------PKP----IEVCMYREP--------- 211
                .|.:.:|.|.                .|.|      .||    |:|..::.|
  Fly   370 LSTYTNAITETVPQERVEQLIAKNFGANRVKHGVRQLCDTGKPLIELIDVARFKAPPHCSSNTSG 434

Human   212 SLHEIGEKQGRSRKSS 227
            |...|......|.|||
  Fly   435 SSSSISSSSSSSSKSS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGF12	NP_066360.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		8/27 (30%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	11..38		8/26 (31%)
		beta-trefoil_FGF12	68..206	CDD:467014	49/181 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..243		5/12 (42%)
bnl	NP_732452.1	beta-trefoil_FGF_Bnl-like	246..377	CDD:466997	40/132 (30%)