Protein Alignment MAPK15 and KDX1

DIOPT Version :9

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_012761.1
• Gene: KDX1 / 853696
• SGDID: S000001644
• Length: 433
• Species: Saccharomyces cerevisiae
• Alignment Length: 389
• Identity: 126/389 - (32%)
• Similarity: 204/389 - (52%)
• Gaps: 47/389 - (12%)

Human    41 VAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQEFGDHPNIISLL--DVIRA 103
            |||:||.:||.:|                   ||.:||.||:.||:....||||:.|.  |::..
Yeast    51 VAIRKIPNAFGNK-------------------LSCKRTLRELKLLRHLRGHPNIVWLFDTDIVFY 96

Human   104 END--RDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSGHVVHRDQKPSNVLL 166
            .|.  ..:||..|.|:.||:.:||....|:|.|.:|..||:|.|.:::||.:|:|.|.||.|:|:
Yeast    97 PNGALNGVYLYEELMECDLSQIIRSEQRLEDAHFQSFIYQILCALKYIHSANVLHCDLKPKNLLV 161

Human   167 DANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGE 231
            :::|.:|:|:|||:.|..: .....|..:..|:.:.||:|||:||:....|..||:||.||||.|
Yeast   162 NSDCQLKICNFGLSCSYSE-NHKVNDGFIKGYITSIWYKAPEILLNYQECTKAVDIWSTGCILAE 225

Human   232 MLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSRPRQTLDALLPPDTSP 296
            :|..:|:|.|...:..|..||:.:..|.||.|..:.|....:.:.|.|:.|.::.:::| |..:|
Yeast   226 LLGRKPMFEGKDYVDHLNHILQILGTPPEETLQEIASQKVYNYIFQFGNIPGRSFESIL-PGANP 289

Human   297 EALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDEWAREADVRPRAHEGVQLSVPEYRSRVY 361
            |||:||:::|.|.|.||::...||:|||:..:|...:|::.:...| ...|.:: |:.|..:.|.
Yeast   290 EALELLKKMLEFDPKKRITVEDALEHPYLSMWHDIDEEFSCQKTFR-FEFEHIE-SMAELGNEVI 352

Human   362 QMILE---------CGGSSGTSREKGPEGVSPSQAHLHK-----PRADP------QLPSRTPVQ 405
            :.:.:         ..|.|.:|.....:.:......:|.     |...|      ||||.|..|
Yeast   353 KEVFDFRKVVRKHPISGDSPSSSLSLEDAIPQEVVQVHPSRKVLPSYSPEFSYVSQLPSLTTTQ 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	114/326 (35%)
		S_TKc	25..325	CDD:214567	106/287 (37%)
KDX1	NP_012761.1	STKc_MPK1	22..355	CDD:173750	114/326 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159046247
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740