Protein Alignment MAPK15 and p38b

DIOPT Version :10

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_477361.1
• Gene: p38b / 34780
• FlyBaseID: FBgn0024846
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 357
• Identity: 135/357 - (37%)
• Similarity: 202/357 - (56%)
• Gaps: 44/357 - (12%)

Human    20 WRNLK-----AYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTF 79
            ::||:     |||.|.|||.|.|...|||||:...|:....|                   :||:
  Fly    24 YQNLQPVGQGAYGQVCKAVVRGTSTKVAIKKLARPFQSAVHA-------------------KRTY 69

Human    80 REITLLQEFGDHPNIISLLDVIRAENDRD-------IYLVFEFMDTDLNAVIRKGGLLQDVHVRS 137
            ||:.||:.. ||.|:|.||||.......|       :|:|...||.|||.:||...|..| ||:.
  Fly    70 RELRLLKHM-DHENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRTQKLSDD-HVQF 132

Human   138 IFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATR 202
            :.||:||..:::||..|:|||.||||:.::.:|.:::.||||||        |.:..:|.|||||
  Fly   133 LVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR--------PAESEMTGYVATR 189

Human   203 WYRAPEVLLSSHRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALG 267
            ||||||::|:...|....|:||:|||:.|:|.||.|||||..:|||.||:|.:..|::|.:..:.
  Fly   190 WYRAPEIMLNWMHYNQTADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRIS 254

Human   268 SGCRASVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPS 332
            |....:.:..|...||:....:. ...:|.|:|||.::|....|||::|.|||.|||::::|.|:
  Fly   255 SESARNYIRSLPVMPRRNFRDIF-RGANPLAIDLLEKMLELDADKRITAEQALAHPYMEKYHDPT 318

Human   333 DEWAREADVRPRAHEGVQLSVPEYRSRVYQMI 364
            ||  :.|.:..::.|..:|.|.::|..|:..:
  Fly   319 DE--QTAALYDQSFEENELPVEKWREMVFSEV 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	133/345 (39%)
p38b	NP_477361.1	STKc_p38	8..353	CDD:143356	135/357 (38%)